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PHYSICAL CHEMISTRY

Course info

  • Course: PHYSICAL CHEMISTRY
  • Year: First year
  • Semester: Second semester
  • Activity type: Integrated educational activities
  • CFU: 6
  • SSD: CHIM/02

Characteristics

TitleCodeCFUSSDSubject areaLecture (Hours)Exercise (Hours)Lab (Hours)
Attività formative affini ed integrativeC6CHIM/02Attività formative affini o integrative48N.D.N.D.

Channels

1
ProfessorDepartment
PAOLA D'ANGELO

Objectives

This course provides an introduction to Thermodynamics, Kinetics and Spectroscopic methods to study biological systems. The different sections of the course will be independent. However, they will be connected by the mathematical principles of kinetics, which are fundamental in describing spectroscopic observations, and by emphasizing the use of spectroscopic applications to detect and characterize biochemical systems.

Textbooks

P.W. ATKINS J DE PAULA ELEMENTI DI CHIMICA FISICA, Zanichelli
R. M. SILVERSTEIN, F.X. WEBSTER IDENTIFICAZIONE SPETTROSCOPICA DI COMPOSTI ORGANICI (Casa ED. Ambrosiana)
C.N. BANWELL-FUNDAMENTALS OF MOLECULAR SPECTROSCOPY (McGraw-Hill)
CANTOR, SCHIMMEL - BIOPHYSICAL CHEMISTRY (Freeman Ed.)

Programme

Thermodynamics:First law of thermodynamics, Entropy and the second law of thermodynamics for closed and open systems. Third Law and Gibbs and Helmholz Energies. Diagrams of state of real mixtures (phase diagrams, equilibrium diagrams, enthalpy andentropy diagrams, multicomponent systems) Mixture property determination (mixture equation of state, mixing properties, partial mole values)Equilibrium conditions (vapour-liquid equilibrium, special cases, Raoult rule, Henry law) Thermodynamics of chemical reactions (reaction enthalpy, reaction equilibrium, calorimetry) Transport Phenomena.Kinetics:This section deals with the theory and application of steady state and transient kinetic techniques to the study of dynamics in biological systems. This section includes the use of steady state kinetic techniques, including inhibitor studies, to investigate enzyme mechanisms. Spectroscopy: This section introduces the principles of spectroscopy and discusses applications of specific techniques to biochemical structure and dynamics. The first part of this section includes: rotational, vibro-rotational spectroscopy, UV/visible absorption, fluorescence and CD. The second part covers nuclear magnetic resonance (NMR). Particular emphasis is placed on the use of spectroscopic techniques to provide information on structural dynamics and molecular interactions.
2
ProfessorDepartment
CESARE MANETTI

Objectives

This course provides an introduction to Thermodynamics, Kinetics and Spectroscopic methods to study biological systems. The different sections of the course will be independent. However, they will be connected by the mathematical principles of kinetics, which are fundamental in describing spectroscopic observations, and by emphasizing the use of spectroscopic applications to detect and characterize biochemical systems.

Textbooks

P.W. ATKINS J DE PAULA ELEMENTI DI CHIMICA FISICA, Zanichelli
R. M. SILVERSTEIN, F.X. WEBSTER IDENTIFICAZIONE SPETTROSCOPICA DI COMPOSTI ORGANICI (Casa ED. Ambrosiana)
C.N. BANWELL-FUNDAMENTALS OF MOLECULAR SPECTROSCOPY (McGraw-Hill)
CANTOR, SCHIMMEL - BIOPHYSICAL CHEMISTRY (Freeman Ed.)

Programme

Thermodynamics:First law of thermodynamics, Entropy and the second law of thermodynamics for closed and open systems. Third Law and Gibbs and Helmholz Energies. Diagrams of state of real mixtures (phase diagrams, equilibrium diagrams, enthalpy andentropy diagrams, multicomponent systems) Mixture property determination (mixture equation of state, mixing properties, partial mole values)Equilibrium conditions (vapour-liquid equilibrium, special cases, Raoult rule, Henry law) Thermodynamics of chemical reactions (reaction enthalpy, reaction equilibrium, calorimetry) Transport Phenomena.Kinetics:This section deals with the theory and application of steady state and transient kinetic techniques to the study of dynamics in biological systems. This section includes the use of steady state kinetic techniques, including inhibitor studies, to investigate enzyme mechanisms. Spectroscopy: This section introduces the principles of spectroscopy and discusses applications of specific techniques to biochemical structure and dynamics. The first part of this section includes: rotational, vibro-rotational spectroscopy, UV/visible absorption, fluorescence and CD. The second part covers nuclear magnetic resonance (NMR). Particular emphasis is placed on the use of spectroscopic techniques to provide information on structural dynamics and molecular interactions.