SERGIO VALENTE

Si riavvisano gli studenti che le lezioni per il Corso di Analisi Chimico-Farmaceutica e Tossicologica I (A-L, CTF, 2 anno)

inizieranno il giorno giovedì 05 ottobre alle ore 09:00 in aula 8 (Ex Ing, CU034) e proseguiranno per tutto il semestre secondo l'orario seguente:

lezioni: lunedì ore 13-15 Ex Ing (CU034), mercoledì ore 11-12 aula B PDT (CU018), gio ore 9-11 Ex Ing (CU034).

A presto

Cordiali saluti

Il docente

Personal information
Name: Sergio Valente
Work address: Piazzale Aldo Moro 5, 00185, Rome (Italy)
Phone number (Lab): 0649913891, 0649913976
Phone number (Office): 0649913237
E-mail address: sergio.valente@uniroma1.it
Education
March 2007
phD “Pasteur Science”, at Department of Drug Chemistry and Technologies, “Sapienza”, University of Rome;
March 2003
University degree in Pharmacy 110/110 cum laude at the above mentioned Department.
Reasearch experiences
From October 2011: Assistant Professor (currently RTD-B) in Medicinal Chemistry at Department of Drug Chemistry and Technologies, Sapienza University of Rome, Italy;
July-2009-May 2011: Post-doc position (REDCAT, Marie Curie project, [European Community's] Seventh Framework Programme [FP7/2007-2013], Grant Agreement No. 215009), LIMBP, Université de la Lorraine-Metz, France.
April 2007-June 2009: contract with Sapienza University for research activity at the Department of Drug Chemistry and Technologies, “Sapienza”, University of Rome.
Main research activity
Design, synthesis and development of small epigenetic modulators of HDACs, SIRTs, HMTs, KDMs, DNMTs) for a new approach to anticancer chemotherapy, neurodegenerative and metabolic pathologies, anti-parasitic treatment.
Abilitations
From July 2007 national abilitation for Pharmacist profession and from January 2015 National Scientific Abilitation (ASN, MIUR) for Associate Professor Position.
Teaching Activity (Faculty of Pharmacy and Medicine, Sapienza University of Rome, Italy).
Holder of the course 2015-2018 “Chemical-Pharmaceutical and Toxicological Analysis I”, II year of master degree in CTF; holder of the course 2012-2013, 2013-2014 and 2014-2015 “Chemical-Pharmaceutical and Toxicological Analysis”, II year of master degree in Pharmacy; holder of the course 2011-2012 “Laboratory of Extractive and Synthetic Preparation of Drugs”, V year of master degree in CTF (Pharmaceutical Chemistry and Technology; member of examination committee, also for Master Degree, integrative lectures and assistance for students; d) tutoring for graduating and PhD students in Medicinal Chemistry.
Congress Communications (oral and posters)
10 oral communications and more than 100 poster communications at National and International Congresses in Medicinal Chemistry.
Awards
Paestum (SA), 11 September 2017, National Prize for Medicinal Chemistry Research received by Medicinal Chemistry Division of Italian Chemical Society.
Technical skills and competences
Advanced and microwave-assisted organic synthesis. Molecular modelling. Windows Vista, XP 2003, 2007, 2010, Windows 7-10, ISIS Draw, Chem Bio Draw 2013, MS Office, Spectrometry analysis (1H-NMR, 13C-NMR, Mass).
Grants
1. Ateneo 2015 Sapienza Project
Title: “Design, synthesis, anticancer evaluation of novel irreversible as well as reversible LSD1inhibitors and development of probes for chemoproteomics of LSD1”
Position in project: Coordinator
2. Ateneo 2014 Sapienza Project
Title: “Enhancer of Zeste Homolog 2 inhibitors: a novel strategy anticancer therapy”
Position in project: Collaborator
3. Ateneo 2013 Sapienza Project
Title: “Regolazione dell'espressione di citochine infiammatorie nel tessuto periprotesico di protesi mammarie siliconiche mediante impiego di inibitori delle istone deacetilasi in un modello sperimentale murino”
Position in project: Collaborator
4. Ateneo 2012 Sapienza Project
Title: “Novel Probes for Sirtuin Enzymes: a Medicinal Chemistry/Chemical Biology Approach”
Position in project: Collaborator
5. European Project EC-GA N°602080; WORK PACKAGE 4, 6, 7
A-PARADDISE 2014-2016
Title: “Anti-Parasitic Drug Discovery in Epigenetics”
Position in project: Collaborator
6. European Project N° 282520; WORK PACKAGE 15, BLUEPRINT 2011-2016
Title: “A BLUEPRINT of Haematopoietic Epigenomes”
Position in project: Collaborator
Reviewer activity
Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Current Topics in Medicinal Chemistry, Expert Opinion on Drug Discovery, Oxidative Medicine and Cellular Longevity, Aging and Disease, Tetrahedron Letters.
Scientific Publications
Author/Co-Author of 103 scientific papers; H-Index: 29, total citations: 3030.
For all scientific publication go to the following link:
https://www.scopus.com/authid/detail.uri?authorId=7102507865