THREE-DIMENSIONAL MODELING

Course objectives

Upon completion of the course the student should be able to: - Understand the principles that govern how drug development in various stages of pre-clinical and clinical research and understand the basic methodology - Learn about the types of Adverse Reactions to Drugs in order to distinguish and assess their seriousness - Know and understand the methodology of pharmacovigilance application utility - Understand the principles of the variability in drug response and know the principles of pharmacogenetics to identify possible applications in clinical practice of Pharmacotherapy - Know the basic methodology for the Analysis of Evaluation of pharmacological interventions - Know the basic tools for the assessment of health-related quality of life and the principles of their use in pharmacoeconomic analysis - Know the organizational possibilities and applications for the safe use of pharmaceuticals

Channel 1
GIOVANNI SEBASTIANO ALEMA' Lecturers' profile

Program - Frequency - Exams

Course program
Clinical pharmacokinetics Adverse drug reactions Principles, methodologies and regulations of pharmacovigilance Variations of the pharmacological response and principles of pharmacogenetics Interactions between drugs Clinical and pre-clinical drug trials Principles and methodologies of pharmacoeconomics Tools for assessing the quality of life Pain therapy
Prerequisites
No particular knowledge is required except for the topics of General Pharmacology received during the three-year Nursing course.
Books
1. Farmacologia clinica, a cura di Luciano M. Fuccella, Emilio Perucca, Cesare Sirtori; Torino UTET, 1998 Biblioteca Comunale di Aprilia, Inv. 7781, Coll. S. G. 615 MUC 53/02 o Fuccella L.M. Cap. 8 La sperimentazione clinica dei Farmaci, pp 74-84 o Velo G. Conforti A. e Leone R., Cap. 12 Farmacosorveglianza, pp 110-19 o Recchia G., Cap. 24 Principi di farmacoeconomia: Qualità della vita e terapia farmacologica, pp 245-63 o Borghi C., Cap. 25 Il rapporto costo/beneficio nelle terapie farmacologiche, pp 265-76 2. Farmacologia. Meccanismo d'azione dei farmaci a cura di Pratt WB. & Taylor P., Bologna, Zanichelli, 2002 - Nebert DW., e Weber WW.,Cap. 7 Farmacogenetica pp 369-419 Biblioteca Comunale di Latina Aldo Manuzio Inventario LTM 49906 Collocazione LTM 615.1 3. Ingelman-Sundberg M., Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future TIPS Vol.25 No.4, 2004, pp 193-200 4. P. G. Davey, M. Malek, T. Dodd, T. MacDonald, Cap. 10 Farmacoeconomia e prescrizione di farmaci, In FARMACOLOGIA E TERAPIA DI AVERY, A cura di Trevor M Speight , Nicholas H.G. Holford, Zanichelli, 2000 On the course website (https://elearning2.uniroma1.it/course/view.php?id=783) there is a complete bibliography for the study of the topics covered in class.
Teaching mode
Frontal lessons. The lessons will end with tests to verify the understanding of the topic or activities to put into practice the topics covered in the lesson
Frequency
In order to be able to take the exam related to the specific integrated course it is necessary to have documented the presence in the classroom of at least 66% of the hours corresponding to the credits assigned to the integrated course.
Exam mode
To Pass the test student must obtain a note of 18/30 for each subject of the integrated teach. Student must possess a sufficient knowledge of the program To obtain a note of 30/30 with distinction student must possess an excellent knowledge of the whole program using a correct terminology to expose the topics.
Lesson mode
Frontal lessons. The lessons will end with tests to verify the understanding of the topic or activities to put into practice the topics covered in the lesson
  • Academic year2025/2026
  • CourseNursing and Midwifery Sciences REPLICA B - LAZIO SUD
  • CurriculumSingle curriculum
  • Year2nd year
  • Semester1st semester
  • SSDBIO/14
  • CFU2