Midwifery REPLICA C - ASL VITERBO

Unit 1. The Universal Features of Cells (4h) Cell theory. Organization of the prokaryotic and eukaryotic cell. The Chemical Components of a Cell, structure and function of biological macromolecules (Polysaccharides, proteins, Fatty Acids, nucleic acids). Enzymes and enzymatic catalysis. Unit 2. Molecular bases of heredity (4h) DNA. The structure of the double helix. DNA replication. DNA repair. Telomerase. Unit 3. How Cells Read the Genome: From DNA to Protein (6h) RNA. Transcription. Processing of eukaryotic mRNAs. The genetic code. tRNAs and ribosomes. Protein synthesis. Control of gene expression in eukaryotes: transcription factors, enhancers, regulation of chromatin structure, post-transcriptional and post-translational control. Unit 4. Internal Organization of the CellStructure and properties of biological membranes. (6h) Cytoplasmic organelles: nucleus, Golgi apparatus, smooth and rough endoplasmic reticulum, ribosomes, mitochondria, lysosomes, peroxisomes. Exocytosis and endocytosis. The cytoskeleton. Unit 5. Cellular communication (2h) Principles of cell signaling. Classes of receptors. Signal transduction. Unit 6. Cell Division (2h) Eukaryotic cell cycle. Mitosis. Sexual reproduction and meiosis

knowledge at secondary school level of biology, chemistry and physics

Elementi di biologia e genetica, P. Bonaldo, C. Crisafulli, R. D'Angelo, M. Francolini, S. Grimaudo, C. Rinaldi, P. Riva, M.G. Romanelli, EdiSES Biologia. Come funziona la vita. James R. Morris, Daniel L. Hartl, Andrew H. Knoll, Robert A Lue, Melissa Michael, ZANICHELLI. Elementi di Biologia, E. P. Solomon, C. E. Martin, D. W. Martin, L. R. Berg, EdiSES Elementi di biologia e genetica. Raven, Johnson, Mason, PICCIN

The course is based on lectures. During the course, self-assessment tests will be proposed followed by discussion.

Mandatory attendance

The exam of the integrated course will consist in the administration of a test with multiple choice and open-ended questions. TEST 1: - Applied Biology: 20 questions - Genetics: 10 questions TEST 2: - Biochemistry: 20 questions -Physics: 10 questions Each question will have 5 possible answers. Only one answer will be correct. Scores for Biology and Biochemistry: Wrong Answer =0; Correct Answer=1.5 Scores for Genetics and Physics: Wrong Answer =0; Correct Answer=3 The time available will be 1 hour and 15 minutes. The exam will be considered passed ONLY if the student has obtained an evaluation greater than or equal to 18/30 in EACH of the 4 modules. The final grade will be the average of the grades of each module weighted by the number of credits (CFU) of each course. If the student does not pass all the modules, the exam must be taken in full in one of the subsequent sessions.

The course is based on lectures and moments in which self-assessment tests will be proposed in the classroom with subsequent discussion of the results. The student will be able to find on the e-learning platform the teaching material (course program, recommended texts, information relating to the course) useful for the preparation of the exam. It is understood that slides and notes are just a guide to the exam topics, but they can never replace the recommended texts and the frontal lessons held by the teacher.