Audioprothesic Techniques

The cell Procariotic cells. Structural and functional organization of eucariotic cells. Cellular chemical components ( mono and polysaccharides, lipids, proteins). Cellular membrane structure and transport. Intracellular organells: endoplasmic reticulum, apparatus del Golgi, lysosomes,peroxisomes, nucleus and chromosomes. Nucleic Acids Nucleotides. Structure and function of RNA (mRNA, rRNA,snRNA and tRNA) and of DNA Replication Bidirectional, semiconservative and semidiscontinous replication. Main enzymes of the replication in vivo: DNA polymerase, DNA topoisomerase, DNA elicase, Primase, DNA ligase The PCR and its applications Transcription of DNA Promoters.RNA polymerase. Eucariotic transcriptional factors Protein synthesis mRNA maturation in the nucleus (Splicing of mRNA). Genetic code. Ribosomes. Mechanism of synthesis of proteins on ribosomes. Mechanisms of gene expression control Transcritional regulation (repressors, activators, eucariotic transcriptional factors). Examples of post-transcriptional controls (alternative splicing) Cellular communication Superficial and intracellular receptors. Transduction signal pathway: AMPc and IP3.Tyrosine chinase receptor. Molecular mechanism of action of: glucagone, insulin and adrenalin. Steroid hormones receptors PROGRAMMA OF GENETIC Cellular division The cellular cycle and its regulation. Mitosis Sexual reproduction and genetic bases of inheritance Meiosis. Mendel experiments and laws. Dominant and recessive characters. Homozygosity and heterozygosity. Characters related to sex. Genic recombination.

Hills et al “Elementi di Biologia e genetica” Zanichelli Stefani, Taddei “Chimica, Biochimica e biologia applicata” Zanichelli Albert et al “L’essenziale di Biologia molecolare della cellula” Zanichelli