Speech and Language Therapy REPLICA ASL RIETI

Key topics of general pathology: 1) Definition of the areas of general pathology. Health and disease concepts. Pathogenesis, etiology, acute and chronic pathologies. 2) Environmental pathology, general characteristics. Pathology caused by physical agents. Radiation. Temperature-related pathologies, burns, frostbite. Pathologies caused by chemical agents. 3) Cellular pathology: Cellular adaptations. Hypotrophy, atrophy, hypertrophy, hypoplasia, hyperplasia; metaplasia; dysplasia. Cell phone damage. Reversible cellular alterations: steatosis; vacuolar degeneration. Cell death: necrosis and apoptosis. 4) Acute inflammation: definition and characteristics. Role of macrophages and fibroblasts. Chemical mediators. Chronic inflammation. Granuloma. Systemic manifestations of inflammation, fever. 5) immunopathology: Recognition of self and non-self. the nonspecific and specific immune response. B and T lymphocytes, antibodies. Complement, dendritic cells and NK cells. autoimmunity, transplants and rejection mechanisms. 6) General oncology. Essential aspects and etiology of tumors, chemical, physical and viral. Mutations. Oncogenes and tumor suppressors. Benign and malignant tumors.

Basic knowledge of cellular, chemical and physical biology acquired during high school courses are considered prerequisites.

one to choose from the following (or similar texts): Pontieri GM. Elementi di Patologia Generale - Per i Corsi di Laurea in Professioni Sanitarie. Edizione Piccin Jeanette Anne Marie Maier, Massimo Mariotti. Elementi di Patologia generale e Fisiopatologia. McGraw-Hill Pontieri G.M. Patologia Generale e Fisiopatologia Generale III o IV ed. Piccin

Attendance at the in-person course is mandatory

A written test will serve as an ongoing evaluation immediately before the end of the lessons. If the result is satisfactory this test will be used for the oral evaluation. Otherwise a normal oral evaluation will take place.

The course takes place with lectures in which students are required a continuous interaction by favoring questions on the topics discussed during the lesson. At the end of the course, one last lesson is dedicated to the evaluation of the comprehension of the topics covered, through a self-assessment test.

INGLESE: Key Topics in General Pathology: 1. Definition and Scope of General Pathology. Concepts of health and disease. Pathogenesis and etiology. Acute and chronic diseases. 2. Environmental Pathology – General Features. Pathology caused by physical agents. Radiation-induced disorders. Temperature-related pathologies: burns and frostbite. Pathology due to chemical agents. 3. Cellular Pathology. Cellular adaptations: hypotrophy, atrophy, hypertrophy, hypoplasia, hyperplasia; metaplasia; dysplasia. Cellular injury. Reversible cellular alterations: steatosis, vacuolar degeneration. Cell death: necrosis and apoptosis. 4. Acute Inflammation. Definition and characteristics. Role of macrophages and fibroblasts. Chemical mediators. Chronic inflammation. Granuloma formation. Systemic manifestations of inflammation, including fever. 5. Immunopathology. Recognition of self and non-self. Nonspecific (innate) and specific (adaptive) immune responses. B and T lymphocytes, antibodies. The complement system, dendritic cells, and natural killer (NK) cells. Autoimmunity, transplantation, and rejection mechanisms. 6. General Oncology. Fundamental aspects and etiology of tumors: chemical, physical, and viral carcinogenesis. Mutations. Oncogenes and tumor suppressor genes. Benign and malignant neoplasms.

Pontieri GM. Elementi di Patologia Generale - Per i Corsi di Laurea in Professioni Sanitarie. Edizione Piccin Jeanette Anne Marie Maier, Massimo Mariotti. Elementi di Patologia generale e Fisiopatologia. McGraw-Hill Pontieri G.M. Patologia Generale e Fisiopatologia Generale III o IV ed. Piccin