Industrial pharmacy REPLICA LATINA

General expected learning outcomes The teaching of Applied Pharmaceutical Chemistry regards the study of the mechanisms of organic reactions involved in drug metabolism and related to the planning and action of drugs. Pre-formulation studies and accelerated storage tests are introduced in order to calculate the shelf-life of the formulations. Industrial methods to separate, sterilize and freeze-dry an active molecule are also studied. Specific expected learning outcomes 1. Knowledge and understanding The student will able to know and understand metabolic processes that drugs understand, valuing the problems of a specific drug, such as toxicity of itself and of its metabolites, as well as any problems of bioavailability and/or stability. The student will acquire knowledge about industrial processes such as filtration, sterilization and freeze-drying. 2. Applying knowledge and understanding The student will be able to value the problems of a drug and to plane pharmaceutical formulations that allow of overcoming these problems, through chemical modifications of the active. The student will be able to determine the stability of the formulation and to value the deadline of the medicine. Starting to the knowledge of the industrial processes of sterilization, filtration and freeze-drying will be able to choose the best methodologies to apply at a specific drug. 3. Making judgements The lessons will be interactive, with a continue comparison between teacher and students about the arguments with the aim to stimulate the interest of the students and to increase their critical sense. This discussion will allow calling back arguments already discussed in other teachings, and connected among them. 4. Communication skills The rating of the student will be made through an oral examination that will have as subject one of the arguments treated during the lessons and applied to a specific drug and this will allow of valuing the making to correlate different aspects and to explain them with adequate scientific language. 5. Learning skills The student will be able to search in the literature and to study critically the scientific papers related to the teaching. In this way, he will be able to elaborate the possible problems related to the drugs and to overcome them as requested by the industrial world.