Medicine and Surgery

The course is meant to provide the fundamental understanding of the molecular basis of human diseases. By the end of the course, the student must: - Know the etiology and the pathogenic mechanisms of human diseases, and the fundamental pathophysiological mechanisms concerning the main organs and systems. - Be able to analyze and to interpret the fundamental etiopathogenic and pathophysiological mechanisms of human diseases. - Be aware that being able to analyze and interpret the fundamental etiopathogenic and pathophysiological mechanisms will be essential for a correct clinical approach to human diseases. MED/04 Learning outcomes: By the end of the course, the student will have to: - Know the molecular mechanisms involved in human cancer development and progression. Know the pathophysiology of metabolism, including atherogenesis and atherosclerosis, and the pathophysiology of major systems. - Be able to discuss the molecular mechanisms of human cancer, and of the general pathophysiology of metabolism and the pathophysiology of major systems. - Be aware that being able to analyze and interpret the molecular mechanisms of human cancer and the general pathophysiology of metabolism and of major systems will be essential for a correct clinical approach to diseases. MED/05 Learning outcomes: By the end of the course, the student will have to: - Know the molecular mechanisms involved in human cancer development and progression. - Know the most relevant laboratory approaches to cancer molecular genetics. MED/13 Learning outcomes: By the end of the course, the student will have to: - Know the pathophysiology of metabolism and the pathophysiology of major systems. - Be able to discuss the general pathophysiology of metabolism and the pathophysiology of major systems. - Be aware that being able to analyze and interpret the molecular mechanisms of the general pathophysiology of metabolism and of major systems will be essential for a correct clinical approach to diseases. MED/46 Learning outcomes: By the end of the course, the student will have to: - Understand the mechanisms of tumorigenesis induced by physical and chemical agents, and experimental methods for the evaluation of the mutagenic potential of chemical and physical agents. Knowing how to choose which methodological approach is more rational based on the type of agent to be analyzed. - Deepen the knowledge of the molecular mechanisms of smoking and alcohol-induced tumorigenesis. - know the pathogenetic mechanisms of cancer associated with the alteration of the mechanisms of apoptosis, and the methodological approaches for the evaluation of apoptosis. Acquire awareness of the complexity and relevance of the mechanisms of deregulation of apoptosis and of the consequences of these alterations on therapeutic approaches. To know the main antiapoptotic mechanisms used by oncogenic viruses.