THREE-DIMENSIONAL MODELING

Course objectives

Module 1 - Microbial biotechnology General expected learning outcomes The course is aimed at deepening microbiological knowledge and the main microbiological techniques useful for the preparation of new pharmaceutical formulations and the screening of molecules with potential antimicrobial activity. The course also aims to provide the skills necessary for the conception and design of scientific research aimed at the development of drugs and vaccines against human pathogens. Specific objectives 1. Knowledge and understanding At the end of the course, the student will acquire skills on the main infectious processes and the development of targeted antimicrobial strategies. Furthermore, the student will acquire specific skills to perform cytotoxicity tests, microbial counting, in order to test molecules with potential antimicrobial activity, using microbiology, biochemistry and molecular biology techniques. 2. Applying knowledge and understanding At the end of the course, the student will acquire skills on the main microbiological, cellular and molecular biology techniques functional for the development of new potential drugs and vaccines with antimicrobial activity. 3. Making judgements Lessons will be interactive. During the lessons the teacher will pursue an effective question strategy in order to stimulate the students’ ability to use a scientific methodological approach to research activities and study. The student will be stimulated to analyse experimental data related to course topics. 4. Communication At the end of the course the student will be able to use an appropriate technical-scientific language to communicate correctly on the topics covered, even with non-specialists or professionals from other disciplines. 5. Learning skills The course is aimed at facilitating a critical and autonomous in-depth study of the topics covered in specialized texts and through consultation of databases and sector-specific platforms.

Channel 1
ROSANNA PAPA Lecturers' profile

Program - Frequency - Exams

Course program
General principles of infectious processes and the development of antimicrobial and antiviral strategies. Antiviral vaccines: inactivated virus, attenuated virus, subunit, recombinant, mRNA. Biotechnological development of vaccines. Antibacterial vaccines: inactivated cells, attenuated cells, toxoids, polysaccharides, protein subunits. Reverse vaccinia: genomics, post-genomics and vaccine development. The development and application of new antimicrobial and antiviral drugs. Viruses of medical relevance and related antiviral strategies. Bacteria of medical relevance and related antimicrobial strategies.
Prerequisites
For a good comprehension of the topics and to achieve the learning objectives, it is important that the student will have acquired knowledge on general microbiology, molecular biology, pathology, pharmacology and biochemistry
Books
Murray, Rosenthal, Pfaller Medical Microbiology 8 th edition (2016), Elsevier Madigan MT., Martinko JM., Stahl DA., Clark DP. “Brock - Biologia dei Microrganismi” vol. 2-3 Pearson
Frequency
Attendance at lessons is not mandatory but strongly recommended.
Exam mode
The exam consists of an oral test in which the student will demonstrate the acquisiton of a good knowledge of all the topics covered in class. The elements taken into consideration for the evaluation are: the knowledge of the subject, the use of an appropriate language, the ability to reason and the ability to expose the topics in a critical and exhaustive way. Sufficient knowledge of the topics covered, in the various parts of the program, is required for passing the exam with minimum grades. To achieve a score of 30/30 cum laude, the student must demonstrate the acquisition of an excellent knowledge of all the topics covered during the course, being able to link them in a logical and consistent way.
Lesson mode
Front lectures by using slides in PowerPoint as a telematic support. At the beginning of each lesson the topics discussed in the previous lesson will be discussed and pointed out in order to allow the student to verify his / her knowledge and the complete comprehension of the topics addressed. The frequency of the course is optional even if strongly recommended. The student will find on the e-learning platform the slides and teaching materials (exam program, recommended texts) useful for the preparation of the exam. The slides are an aid to the study, and should not replace the recommended texts and lectures given by the teacher.
  • Academic year2025/2026
  • CoursePharmaceutical Biotechnology
  • CurriculumSingle curriculum
  • Year1st year
  • Semester2nd semester
  • SSDMED/07
  • CFU6