MASTER'S THESIS AT THE ISTITUTO SUPERIORE DI SANITA’
A master's thesis is available from the "Centro Nazionale per la Salute Globale dell’Istituto Superiore di Sanità" on the topic:
Study of the blockade of chemokine receptors CCR2 and CCR5 in cellular models of SARS-CoV-2 and HIV-1 infection.
Contact: Dr. Laura Fantuzzi - laura.fantuzzi@iss.it -0649903001
CCR2 and CCR5 are chemokine receptors that play a key role in the migration of monocytes/macrophages and T lymphocytes. They are implicated in the pathophysiology of various human diseases, including viral infections and conditions characterized by an inflammatory component. In vitro cellular models of HIV-1 and SARS-CoV-2 infection will be used to study the effect of blocking these receptors, using antibodies and antagonistic drugs, on viral replication and the antiviral and inflammatory response. The research will be conducted using cellular, molecular, and biochemical techniques.
The candidate must have a bachelor's degree in Biological Sciences or Biotechnology.
