Neuroscience and Mental Illness

Course objectives

General objectives. The course aims to provide the theoretical-methodological knowledge necessary to critically orient oneself in neuroscience about mental disorders and their treatment. The main expected learning objective is for the student to learn to extrapolate relevant and valuable results from the neuroscientific literature for the professional practice of the psychologist. Specific objectives. The specific objectives of the course will be to encourage the development of skills suitable for applying the knowledge learned into particular application contexts. Some topics addressed will be the diathesis-stress etiological model and the interaction between genetic, epigenetic, environmental, and developmental risk factors. The biopsychosocial model and the evolutionary model of affective neuroscience. Limits of preclinical research based on categorical nosography: the Research Domain Criteria (RDoC) model. Epidemiology, risk factors, and psychobiological correlates of the most common mental disorders: Psychotic disorders, Bipolar disorder, Depressive disorders, Anxiety disorders, Obsessive-compulsive disorder. Fronto-limbic systems, incentive salience, and self-regulation of behavior. Neural bases and etiological role of Pavlovian and operant learning: reinforcement, avoidance and protective behaviors; conditioned fear and its extinction. Behavior modification and its neural bases: notes on functional analysis; differential reinforcement; counter-conditioning; exposure and response prevention.

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DAVID CONVERSI Lecturers' profile

Program - Frequency - Exams

Course program
Introduction to the course: objectives, lectures and laboratory. Psychopathology and the mind-body problem: limits of non-reductionist physicalism. Metatheoretical assumptions: the diathesis-stress etiological model; interaction between genetic, epigenetic, environmental and developmental risk factors; The biopsychosocial model; The evolutionary model of affective neuroscience. Limits of preclinical research based on categorical nosography (DSM-5 and ICD-11): the Research Domain Criteria (RDoC) model. Epidemiology, risk factors, neurobiological correlates and neurochemical hypotheses for some of the most common mental disorders: Psychotic disorders Bipolar disorder; Depressive disorders; Anxiety disorders; Obsessive compulsive disorder. Fronto-limbic systems, incentive salience and self-regulation of behavior Neural bases and etiological role of Pavlovian and instrumental learning: reinforcement, avoidance and protective behaviors; conditioned fear and extinction. Behavior modification and neural bases: notes on functional analysis; differential reinforcement; counter-conditioning; exposure and response prevention. Neuroplasticity as a biological foundation of behavioral interventions.
Prerequisites
In order to understand the topics covered, it is recommended to have passed the following exams: Psychodiagnostics, Psychobiology of stress, Advanced course of Psychobiology, Psychobiology of addictions.
Books
Selection of scientific articles and literature reviews in English.
Frequency
Attendance not mandatory, but recommended.
Exam mode
Written test with multiple choice questions for the frontal part. Essay or oral presentation for the laboratory part.
Lesson mode
Lectures, seminars; E-learning activities.
  • Lesson code10616741
  • Academic year2025/2026
  • CourseCognitive Neurosciences and Psychological Rehabilitation
  • CurriculumNeuroscienze Cognitive Sperimentali (percorso formativo valido anche ai fini del rilascio del doppio titolo italo-colombiano)
  • Year1st year
  • Semester2nd semester
  • SSDM-PSI/02
  • CFU6