CLAUDIA STEFANUTTI

Curriculum Vitae et studiorum

Name/Degree: Claudia Stefanutti, M.D., Ph.D., Assistant Professor of Internal Medicine

Title/Institution: Dept. of Molecular Medicine - Immunohematology and Transfusional Medicine – Extracorporeal Therapeutic Techniques Unit - Lipid Clinic and Atherosclerosis Prevention Centre - “Sapienza” University of Rome. ’Umberto I’ Hospital
Street Address: 155, Viale del Policlinico
City: Rome State/Province/Country: Italy EU Postal Code: 00161
Phone: ++39 06 49970578 Fax: ++39 06 49970141 E-mail: plasmaferesi@tin.it; cstefanutti@alice.it; claudia.stefanutti@uniroma1.it
Ordine provinciale di Roma dei Medici Chirurghi e degli Odontoiatri (Licence): M37342 (since June 26,1986);
Essential Good Clinical Practice January 11, 2012 (Certified)
Online Learning Method by Phase Forward, Inc.INF 4.6 PISignature –Modules March 5, 2012 (Certified)
Clin Track EDC Clinical Trials Management System - Data Management / Electronic Data Capture (DM/EDC) 2012 (Certified)
Tested as per 49CFR 172.700/IATA 1.5 Mayo Clinic Medical Laboratories
MD received from: University “La Sapienza” of Rome Year: 1981
Specialty 1: Liver and Metabolic Diseases
Specialty 2: Emergency Surgery
PhD (Experimental Medicine: Atherosclerosis) received from: University of Siena Year: 1988
Present Position: Assistant Professor of Internal Medicine, Head of ‘Extracorporeal Therapeutic Techniques Unit’ - Immunohematology and Transfusional Medicine – Department of Molecular Medicine - Lipid Clinic and Atherosclerosis Prevention Centre
Prior Positions: Research Fellow (Technologist)

Mentorship and International Scientific Collaboration:

1983 16th Ten Day International Teaching Seminar on Cardiovascular Epidemiology and Prevention. International Society and Federation of Cardiology, Susono (Japan). 1988 Doctorate in experimental medicine: Atherosclerosis. 1995 Scientific collaboration: Department of Cardiology and Artificial Organs. Koga Hospital. Kurume. Japan. 1996 By invitation of Dr. Josè Miguel Boquinhas, Director of Internal Medicine and Nephrology Departments of ‘Santa Cruz’ Hospital and Dr. Egidio Pedro, Institute of Cardiology and Biochemistry Department, University of Lisbon (Portugal), to coordinate the development of the first Center for LDL-apheresis in Portugal, and as advisor for medical personnel training. 2000-2001 Scientific collaboration with Professor Thomas Bosch, Department of Nephrology, University of Meunchen, Germany, ‘Grosshadern’ Hospital devoted to the development of a new method for ‘low-dose citrate anticoagulation DALI LDL-apheresis’, co-validated in Meunchen and Rome. 2002-2002 Subsequent scientific collaborations: Pediatric Endocrinology and Diabetology. Hôpital des Enfants. University of Geneva. Switzerland. 2003 New children's day centre. Hammersmith Hospital. London. Great Britain. Inherited Metabolic Disorders Clinical. Birmingham Children’s Hospital. Great Britain. 2009 University of Pennsylvania, Department of Medicine. Professor Marina Cuchel Philadelphia U.S.A., “A Phase III, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Lomitapide (AEGR-733) plus Current Maximal Tolerated Therapy (MTT) in Subjects with Severe Refractory Heterozygous Familial Hypercholesterolemia”. 2010 Scientific advisor for LDL-apheresis; Griffith University School of Medicine Southport, Queensland (Australia), Professor Ian Hamilton-Craig (Internal Medicine and Preventive Cardiology) on “Familial Hypercholesterolemia: a Model Care for Australia”. 2011-2012 Scientific and editorial collaboration with Prof. Ulrich Julius. University "Carl Gustav Carus" of Dresden. Dresden, Germany. 2013 Baltic Apheresis Working Groups Eco4Life – Rostock, Germany. 2013 Prof. JJP Kastelein, Head of Department of Vascular Medicine Academic Medical Center - University of Amsterdam The Netherlands. 2013 Dr. Mariko Harada-Shiba, Director Department of Molecular Innovation in Lipidology National Cerebral and Cardiovascular Center Research Institute, Osaka,Japan. 2013 Dr. Handrean Soran, Central Manchester University Hospitals NHS Foundation Trust 2014 Scientific and editorial collaboration with Prof. Thompson Gilbert R. Clinical Lipidology, Hammersmith Hospital, Imperial College London, Ducane Road, London W12 0NN, UK 2014 Prof. Eric Sijbrands, Head of Erasmus Cardiovascular Genetics Department - Erasmus MC, Rotterdam, The Netherlands 2015 Prof. Watts Gerald F Royal Perth Hospital, School of Medicine and Pharmacology, The University of Western Australia.

2010 Designated Full Member of the International Society of Cytokines

2011 European Board Trustee of the International Society for Apheresis (ISFA).

2006-2012 Italian Multicenter Study on LDL-apheresis Working Group Coordinator

2013 Multidisciplinary International Group for Hemapheresis Therapy and Metabolic Disturbances Contrast – Italy / Acronym: MIGHTY MEDIC – Coordinator

2009 Italian Society of Internal Medicine

2013 Gruppo di Studio delle Malattie Dismetaboliche e dell’Aterosclerosi

2015 Full Member of the European Atherosclerosis Society

2015/2016 President of the Multidisciplinary International Group for Hemapheresis TherapY and MEtabolic DIsturbances Contrast (MIGHTY MEDIC) – Global Scientific Society

Peer reviewer

For the evaluation of research products in the framework of the Italian Evaluation of Research Quality exercise (VQR 2004-2010) National Agency for the Evaluation of Universities and Research Institutes

Cochrane Renal Group

HEART UK The Cholesterol Charity

National Science Centre (Narodowe Centrum Nauki - NCN; http://www.ncn.gov.pl).

Editorial Board Member / Peer Reviewer of the following Journals:

Journal of Biomedical Research, BMC Gastroenterology, Journal of Pharmacology & Clinical Toxicology, Clinical and Research in Hepatology and Gastroenterology, Expert Opinion on Pharmacotherapy, Medicinal Chemistry, Pediatrics, Dove Medical Press Journals, Therapeutic Apheresis and Dialysis, Recent Patents on Endocrine Metabolic & Immune Drug Discovery Lipids, Artificial Organs, Cytokine, Thyroid: official journal of the American Thyroid Association, European Heart Journal, JOP: Journal of the pancreas, Journal of Clinical Apheresis, Current Medicinal Chemistry, European Journal of Internal Medicine, New England Journal of Medicine, Saudi Medical Journal, Medical Principles and Practice, Journal of Membrane and Separation Technology, Journal of Crohn's and Colitis, World Journal of Gastroenterology, Express Submission and Peer-review System (ESPS), QJM: An International Journal of Medicine, Nutrients, Case Reports in Critical Care, BMJ Case reports

Courses Organized (or participated only as Invited Speaker and/or Chair; international and national levels only):

In the Workshops of the 4th International Congress of the World Apheresis Association. “Plasma Lp(a) profile in patients with familial hypercholesterolemia treated by DSC LDL-apheresis and plasma ex-change”. Susono, Sapporo, Japan, 1992.
Italian Research Council. Hearing on: ”L’aferesi terapeutica: necessita’ di ricerca finalizzata. LDL-aferesi: prospettive di ricerca.” Special Project ‘’Prevention and Control of Disease Determinants - FATMA’’. Consiglio Nazionale delle Ricerche. Roma, October 28, 1994.
World Apheresis Association 6 Th International Congress pediatric LDL apheresis: Italy’s largest clinical experience. Florence, November 11-14, 1996.
II DALI Symposium. “ History of LDL-apheresis”. Munich, March 21-22, 1998.
International Course on Lipids: Update. Coronary Heart Disease in Diabetes Mellitus. President: Prof. H. Saldanha. Moderators: M. Arca, C. Stefanutti, and L. Santos. Cascais, Portugal, March 7-8, 1998.
Italian Society for Atherosclerosis (Regional): Experimental and clinical research on atherosclerosis in region Lazio. University of ‘Torvergata’. Rome, May 9, 2003.
IV National Congress on Therapeutic Apheresis. Italian Society of Nefrology, Society of Arteriosclerosis, Italian Society of Rheumatology, Italian Society of Hemapheresis and Italian Society of Anesthesiology and Intensive Therapy. Montesilvano, Pescara, October 3-4, 2003.
5th World Congress of the International Society for Apheresis”, Rostock (Germany) May 4-7, 2005
LIPIDCLUB 2005 I Meeting di aggiornamento “Diagnosi e Terapia delle Dislipidemie” – Roma, 05 novembre 2005
I Convegno Nazionale” Aterosclerosi dal bambino all’adulto”- Roma-25 Marzo 2006
SISA XX Congresso Nazionale –Bologna-19 Novembre 2006
Aferesi terapeutica delle gravi dislipidemie: stato attuale e prospettive
S.I.S.A. Congresso Nazionale, Perugia, Novembre 2007
1° International Symposium LDL-apheresis and Immunoadsorption
Saint-Cyr-sur-Mer, France October 24-26, 2008
SIdEM Corso Nazionale di Aggiornamento, Bergamo, 22-24 Maggio 2008
S.I.S.A. Congresso Nazionale Roma, 22 Novembre 2008
Lipidclub 2008, Roma
4° Convegno Nazionale Aterosclerosi dal bambino all’adulto. Trieste, 8-9 Maggio 2009
LIPIDCLUB & Therapeutic Apheresis 2009 Interdisciplinary Educational Forum Updating in Apheresis and Atherosclerosis Research Rome,May 15, 2009 (*)
(*):The 2009 2nd Italian Consensus Conference on LDL-apheresis was held in Rome, Italy, May 15, 2009 in the Interdisciplinary Updating Course “Lipidclub 2009”. “La Sapienza” University of Rome; ‘ Umberto I’ Hospital.
XXIII Congresso Nazionale S.I.S.A. Società Italiana per lo Studio dell’Arteriosclerosi - Roma, 25/28 Novembre 2009
“Familial Hypercholesterolemia: New Aspects of Diagnosis and Treatment”, Vienna (Austria) November 20 – 21, 2009
1st Dresden International Symposium on Therapeutic Apheresis
September 4 – 5, 2009 (Germany)
SINUT (Società Italiana di Nutraceutica) 1° CONGRESSO NAZIONALE Milano 11-13 febbraio 2010
LIPIDCLUB & Therapeutic Apheresis 2010 Interdisciplinary Educational Forum Updating in Apheresis and Atherosclerosis Research Rome,May 7, 2010
V Congresso Nazionale AMEC (Associazione per la terapia delle malattie metaboliche e cardiovascolari. Latina, 17-18 settembre 2010
VII CONGRESSO NAZIONALE DI AFERESI TERAPEUTICA- S.I.N. Alghero 28-29 Maggio 2010
“XV Corso Nazionale di Aggiornamento SIdEM” Roma, 23-25 Settembre 2010
XXIV Congresso Nazionale S.I.S.A. Società Italiana per lo Studio dell’Arteriosclerosi – Roma, 24-27 Novembre 2010
8th International Society for Apheresis Congress
Vienna, September 14-17, 2011
2° Dresden International Symposium on Therapeutic Apheresis March 15-17, 2012
7th Lipidclub & Therapeutic Apheresis 80th EAS Satellite Symposium, SanGemini, Italy, May 23-24, 2012
ESAO 2012 Rostock (Germany) Sept 26-29, 2012. Experiences from the Italian LDL-apheresis-Study working group.
Kaneka Pharma Europe N.V. (KPE) German Branch opening ceremony Scientific Workshop - Frankfurt, Germany, October 2, 2012
1st World Congress of Clinical Lipidology “Lomitapide – microsomal transfer protein inhibition as a treatment of HoFH” Budapest Dec 6-9th, 2012
Baltic Working Groups Eco4Life – Meeting. “New Lipid Lowering Drugs – Chances and Limitations” Rostock, Germany, March 22-23, 2013
Therapeutic Apheresis Conference – “Italian Multicenter Study on Lipoprotein Apheresis Working Group 2009 Survey (2013). A look to the future” Saint-Petersburg, Russia, April 26-28, 2013
9th ISFA. “Lomitapide: mechanism of action” Hangzhou, China. May 9-12, 2013
Baltic Apheresis Working Group, Szczecin, Poland Oct 14-15, 2013 Severe dyslipidemia in Italy – the future role of apheresis therapy
The 8° - Krag – Atherothrombosis Conference (Poland) Lomitapide – a new therapeutic approach for lowering LDL-cholesterol Krag, Poland, October 18, 2013
Selective apheresis role in modulating cytokine profile in severe dyslipidemia
From the Italian Multicentre Study for LDL-apheresis Working Group experience to the MIGHTY MEDIC International Network WWW.MIGHTYMEDIC.ORG
2nd International Symposium Fresenius Medical Care “Therapeutic Apheresis” October 25 – 27, 2013 - Sorrento, Italy – EU
UK National Lipoprotein Apheresis Conference, 7th March 2014 – Manchester , UK
3rd Dresden International Symposium on Therapeutic Apheresis, March 13 – 15, 2014 – Dresden, Germany
9th LIPIDCLUB & Therapeutic Apheresis 2014 – Interdisciplinary Educational Forum - Rome, June 6-7 2014
XLI Annual ESAO Congress European Society for Artificial Organs - ROMA September 17-20, 2014
Lp(a) Update. Essen (Germany) November 7-8 2014
Physicians’ Academy for Cardiovascular Education (PACE) Expert meeting “LDL-c Targets in HoFH” December 3, 2014 Amsterdam, Netherlands
The 2nd World Congress on Clinical Lipidology Vienna (Austria) 5th - 7th December 2014

Member / Advisor

FH CTA consortium – The consortium consists of 30 participants, mainly physicians treating large numbers of FH patients, from 16 countries -

Expert Working Group on Apheresis, Paris, 4th November 2014 - Aegerion Pharmaceuticals

Grants Received:

- 1983-1986 Progetto Finalizzato “Medicina Preventiva e Riabilitativa” (CNR): Special project
- 1986 Ministero della Sanità (MS): Research project
- 1991-1995 Progetto Finalizzato “Prevenzione e Controllo dei Fattori di Malattia” (CNR). Special project
- 1989-1991 Multicenter trial on the efficacy and safety of dextrane sulfate cellulose Low-Density Lipoprotein -apheresis in patients affected by homozygous familial hypercholesterolemia.
- 1996 Progetto Finalizzato “Prevenzione e Controllo dei Fattori di Malattia” (CNR). Special project
- 1996 Clinical Trial: FACT Study Fluvastatin Alone and in Combination Treatment N. LES-I-05 Sandoz.
- 1998 C1q Immunoadsorption: cellular immune reaction in patients with immune complex-mediated diseases. Code C1q-P. Open Feasibility Study. Fresenius AG, St. Wendel,Germany.
- 1999-2000 Research project: DALI low-dose citrate LDL-apheresis: evaluation of a new hemoperfusional plasmapheresis system (ART). Fresenius AG, St. Wendel, Germany.
- 2000-2001 Clinical Trial: Multicenter randomized double blind-placebo study on cerivastatin (0.4 mg/d) vs simvastatin (20 mg/d) in patients with Primary hypercholesterolemia. BAY w 6228/IMPACT Trial N. 10156. Bayer.
- 2002-2003 Clinical Trial: A multicenter, double-blind, placebo-controlled study to evaluate the safety and efficacy of MK-0767 monotherapy in patients with type 2 diabetes mellitus. Merck & Co. Inc. U.S.A.
- 2006-2008 Italian Multicenter Study (IMS) on LDL-apheresis (LDLa) Working Group. B.Braun
- Avitum Italy, Caridian-BCT Europe, Fresenius Medical Care Germany, Fresenius Medical Care, Italia
- 2009 The 2009 2nd Italian Consensus Conference on LDL-apheresis. Kaneka Pharma Europe
- 2009-2010 Clinical Trial: “A Phase III, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Lomitapide (AEGR-733) plus Current Maximal Tolerated Therapy (MTT) in Subjects with Severe Refractory Heterozygous Familial Hypercholesterolemia”. Aegerion, USA
- 2010-2011 Cytokines Profile in Serum of Homozygous Familial Hypercholesterolaemia is changed by
LDL-apheresis - Kaneka Pharma Europe N.V. (Japan)
- 2011 Apheresis-inducible cytokines pattern change in severe, genetic dyslipidemias. Fresenius
Medical Care (Germany)
- 2011 Clinical trial: "Modifying Orphan Disease Evaluation (MODE) Study: A multicenter, open-label study of the effects of CER-001 on plaque volume in subjects with Homozygous Familial Hypercholesterolemia (HoFH)”. Cerenis™ Therapeutics, S.A.
- 2012 Clinical trial: ”A 52-Week Open-Label Extension and Safety Study of Pitavastatin in High-Risk Hyperlipidaemia in Childhood”. Kowa Research Europe Ltd
- 2012 Clinical Trial: “A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients with Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol”. Genzyme Corporation
2012 Clinical Trial R727-CL-1110 A Randomized, Double-Blind Study of the Efficacy and Safety of REGN727 Added-on to Atorvastatin versus Ezetimibe Added-on to Atorvastatin versus Atorvastatin Dose Increase versus Switch to Rosuvastatin in Patients Who are Not Controlled on Atorvastatin. Regeneron, USA
2012 Clinical Trial R727-CL-1118 A Randomized, Double-Blind Study of the Efficacy and Safety of
REGN727 Added-on to Rosuvastatin versus Ezetimibe Added-on to Rosuvastatin versus
Rosuvastatin Dose Increase in Patients Who are Not Controlled on Rosuvastatin. Regeneron USA
2012 Clinical Trial Randomized, double-blind, placebo-controlled, parallel-group study in patients
with homozygous familial hypercholesterolemia (HoFH). Regeneron, USA
2012 Heterozygous Familial Hypercholesterolemia (HeFH) Apheresis Advisory Panel. October 11th,
2012, New York LDL APHERESIS STUDY STEERING COMMITTEE MEETING - PROJECT CODE
28005 – Regeneron, USA. Advisory Board
2012 Combined Lomitapide and LDL-apheresis Treatment in Homozygous Familial
Hypercholesterolemic Subjects Study Project - Aegerion, USA - Advisory Board
2012 Genzyme Global Advisory Board 5-6 December, Budapest, Hungary - Advisory Board
2013 “Treatment of Symptomatic HyperLp(a)lipoproteinemia with Lipoprotein-apheresis.The Italian
reality” Osaka, Japan, May 15 2013 – Advisory Board
2013 PACE Roundtable - Exploring the clinical benefits of MTP inhibition in HoFH – Amsterdam
(Holland) September 2, 2013 - Advisory Board
2013-2014 European Research Collaboration Agreement between “Sapienza” University of Rome –
Dept. of Molecular Medicine and Fresenius Medical Care Germany Deutschland GMBH. Scientific
Advisor and Research Leader
2014 Phase 3 severe hypertriglyceridemia study (CS5) and phase 3 Familial Chylomicronemia Syndrome (FCS) study (CS6) both evaluating the efficacy of a subcutaneous investigational drug as compared to placebo on the change in fasting triglycerides (TG) from baseline. National Coordinator

- Curriculum Vitae (continued)
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- Publication Highlights
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- Book Chapters
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- Claudia Stefanutti, Claudia Morozzi: Low Density Lipoprotein Apheresis. 04/2013: pages 12; , ISBN: 978-1-62257-701-9
- Stefanutti, Vivenzio, Mazzarella: Lipoprotein And Hemocoagulatory Parameters During Therapeutic Plasmapheresis In Homozygous And Heterozygous Familial Hypercholesterolemia. 01/1993: pages 223-233; , ISBN: 3805558430
- Stefanutti, Perrone, Galoppi: Long-Term Effect On Plasma-Lipid And Lipoprotein Profile Of Transdermal And Oral Replacement Therapy In Postmenopausal Women. 01/1992: pages 365-368;
- Stefanutti, Di Giacomo, Vivenzio: Gemfibrozil Alone And Combined With Cholestyramine In The Treatment Of Primary Hyperlipoproteinemia. 01/1992: pages 583-586;
- Stefanutti, Mazzarella, Vivenzio: Extracorporeal Atherogenic Lipoprotein Removal In Patients With Homozygous Familial Hypercholesterolemia. 01/1992: pages 333-344;
- Angelico, Capocaccia, Stefanutti C, GREPCO: The Grepco Studies - Methodology, Prevalence and Incidence Data. 01/1991: pages 12: 3-6;
- Angelico, Capocaccia, Stefanutti C, GREPCO: Serum-Lipids And Gallstone Disease. 01/1991: pages 12: 121-127;
- Attili, Capri, Repice, Stefanutti C: The Natural-History of Gallstones - The Grepco Experience. 01/1991: pages 12: 47-50;
- Stefanutti, Isacchi, GC, Mazzarella: Variables Involved In The Treatment Of Severe Hyperlipoproteinemias By Combined Drug and LDL-Apheresis Treatment. 01/1990: pages 498-505;
- Stefanutti, Isacchi, GC, Masci: Dextran Sulfate Cellulose LDL-Affinity Apheresis In The Treatment Of Severe Familial Hypercholesterolemia And Nonfamilial Hyperlipoproteinemia - A Clinical Report On 12 Cases. 01/1990: pages 253-267;
- Bucci, Azzarri, Stefanutti C: Smoking-Habits and Risk of Asymptomatic Carotid Lesions in a Free-Living Population-Sample. 01/1990: pages 954: 337-342;
- Bucci, Antonini, Azzarri, Stefanutti C: Atherosclerotic Carotid Lesions in a Sample of Free Living Population - B-Mode Evaluation of Prevalence and Incidence. 01/1989: pages 817: 633-636;
- Claudia Stefanutti, Urbinati G.C., Perrone G., Mancone M., Pacioni F., Tesseri E., Zichella L., Ricci G: Serum lipid profiles in women using three different oral contraceptives: a different atherogenic risk?. 01/1987: pages 1095-1101;
- Claudia Stefanutti, Bucci A., Lalloni L., Chiaromonte C, Scarno A., Ricci P., Azzarri L., Ricci G: B-mode echography: a new approach to the Epidemiology of Atherosclerotic Disease?. 01/1986: pages 529-534;
- Claudia Stefanutti, Calvieri A, Fazio S., Fanelli V.: Effects of the diet supplementation with glucomannan fibers on type IIa e IIb monogenic and polygenic hypercolesterolemia: a clinical study. 01/1986: pages 793-798;
- Claudia Stefanutti, Bucci A., Lalloni L.: Clinica e diagnostica delle iperlipoproteinemie. 01/1986: pages 113-117;
- Claudia Stefanutti, Fazio S., Arca M., Angelico F., Calvieri A., Pacioni F, Fanelli V: Bezafibrate in the treatment of primary hyperlipidemias (HLP): further evaluation. 01/1986: pages 847-851;
- Claudia Stefanutti, GREPCO: Decreased serum high-density-lipoprotein cholesterol and risk of cholelithiasis. 01/1982: pages 39-43;
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- Journal Publications
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- Stefanutti C, Mazza F, Steiner M, Watts GF, De Nève J, Pasqualetti D, Paal J. Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia. Mediators Inflamm. 2016;2016:4739512.
- Sahebkar A, Simental-Mendía LE, Stefanutti C, Pirro M. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis. Pharmacol Res. 2016 Mar;105:198-209.
- Averna M, Cefalù AB, Stefanutti C, Di Giacomo S, Sirtori CR, Vigna G. Individual analysis of patients with HoFH participating in a phase 3 trial with lomitapide: The Italian cohort. Nutr Metab Cardiovasc Dis. 2016 Jan;26(1):36-44.
- Dadkhah M, Stefanutti C. Hijacked journals are emerging as a challenge for scholarly publishing. Pol Arch Med Wewn. 2015;125(10):783-4. No abstract available.
- Braamskamp MJ, Stefanutti C, Langslet G, Drogari E, Wiegman A, Hounslow N, Kastelein JJ; PASCAL Study Group. Efficacy and Safety of Pitavastatin in Children and Adolescents at High Future Cardiovascular Risk.J Pediatr. 2015 Aug;167(2):338-43.e5. doi: 10.1016/j.jpeds.2015.05.006. Epub 2015 Jun 6.
- Stefanutti C, Blom DJ, Averna MR, Meagher EA, Theron Hd, Marais AD, Hegele RA, Sirtori CR, Shah PK, Gaudet D, Vigna GB, Sachais BS, Di Giacomo S, du Plessis AM, Bloedon LT, Balser J, Rader DJ, Cuchel M; Phase 3 HoFH Lomitapide Study Investigators. The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a Phase 3, single-arm, open-label trial. Atherosclerosis. 2015 Jun;240(2):408-14.
- Michael M Page, Claudia Stefanutti, Allan Sniderman, Gerald F Watts: Recent advances in the understanding and care of familial hypercholesterolaemia: significance of the biology and therapeutic regulation of proprotein convertase subtilisin/kexin type 9. Clinical science 02/2015;
- G. Kees Hovingh, Loek P. Smits, Claudia Stefanutti, Handrean Soran, See Kwok, Jacqueline de Graaf, Daniel Gaudet, Constance H. Keyserling, Heather Klepp, Jennifer Frick, John F. Paolini, Jean-Louis Dasseux, John J.P. Kastelein, Erik S. Stroes: The effect of an Apolipoprotein A-I- containing HDL-mimetic Particle (CER-001) on carotid artery wall thickness in Patients with Homozygous Familial Hypercholesterolemia.
- Claudia Stefanutti, Ulrich Julius: Treatment of primary hypertriglyceridemia states – general approach and the role of extracorporeal methods.
- Barbara Sjouke, G. Kees Hovingh, John J.P. Kastelein, Claudia Stefanutti: Homozygous Autosomal Dominant Hypercholesterolemia: Prevalence, Diagnosis, and Current and Future Treatment Perspectives. Current Opinion in Lipidology 01/2015;
- Claudia Stefanutti, G. D’Alessandri, A. Petta, M. Harada-Shiba, U. Julius, H. Soran, P. M. Moriarty, S. Romeo, E. Drogari, B. R. Jaeger, Giorgio Bianciardi: First on-line survey of an international multidisciplinary working group (MightyMedic) on current practice in diagnosis, therapy and follow-up of dyslipidemias.
- Claudia Stefanutti, Giancarlo Labbadia, Vasilios G. Athyros: Hypertriglyceridaemia, Postprandial Lipaemia and non-HDL cholesterol. Current Pharmaceutical Design 10/2014; DOI:10.2174/1381612820666140620120130
- Claudia Stefanutti: Targeting MTP for the treatment of homozygous familial hypercholesterolemia. Clinical Lipidology 06/2014; 9(3):369-381. DOI:10.2217/clp.14.17
- Claudia Stefanutti: Therapeutic Plasmapheresis. A gate to an effective treatment of severe pathological conditions. Advances in Bioscience and Clinical Medicine 06/2014; DOI:10.7575/aiac.abcmed.14.02.02.10
- Claudia Stefanutti: Targeting Microsomal Triglyceride Transfer Protein for the treatment of Homozygous Familial Hypercholesterolaemia. Clinical Lipidology 06/2014;
- Claudia Stefanutti & Gilbert R. Thompson: Lipoprotein Apheresis in the Management of Familial Hypercholesterolaemia: Historical Perspective and Recent Advances
- Claudia Stefanutti: Therapeutic Plasmapheresis. A gate to an effective treatment of severe pathological conditions. Advances in Bioscience and Clinical Medicine 06/2014;
- Roberto Brunelli, Marco De Spirito, Giampiero Mei, Massimiliano Papi, Giuseppina Perrone, Claudia Stefanutti, Tiziana Parasassi: Misfolding Of Apoprotein B 100, Ldl Aggregation And 17-Beta-Estradiol In Atherogenesis.. Current Medicinal Chemistry 01/2014; DOI:10.2174/0929867321666140120114944
- Claudia Stefanutti, Giancarlo Labbadia, Claudia Morozzi: Severe hypertriglyceridemia-related acute pancreatitis: myth or reality?. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 08/2013; 17(4):464-5.
- Claudia Stefanutti, Fabio Mazza: Efficacy and Safety of Dif1stat ® for the Treatment of Secondary Dyslipidemia in Chronic Kidney Disease. Life Sciences 07/2013;
- Claudia Stefanutti, Giancarlo Labbadia, Claudia Morozzi: Severe hypertriglyceridemia-related acute pancreatitis.. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 04/2013; 17(2):130-7.
- Claudia Stefanutti, Claudia Morozzi, Serafina Di Giacomo: Italian multicenter study on low-density lipoprotein apheresis working group 2009 survey.. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 04/2013; 17(2):169-78.
- Claudia Stefanutti: Treatment of severe genetic dyslipidemia: where are we going?. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 04/2013; 17(2):122-3.
- Claudia Stefanutti, Maria Gozzer, Livia Pisciotta, Patrizia D'Eufemia, Giovanna Bosco, Claudia Morozzi, Francesco Papadia, Manhaz Shafii, Serafina Di Giacomo, Stefano Bertolini: A three month-old infant with severe hyperchylomicronemia: Molecular diagnosis and extracorporeal treatment.. Atherosclerosis. Supplements 01/2013; 14(1):73-6.
- C Stefanutti, U Julius: Lipoprotein apheresis: State of the art and novelties.. Atherosclerosis. Supplements 01/2013; 14(1):19-27.
- Marina Cuchel, Emma A Meagher, Hendrik du Toit Theron, Dirk J Blom, A David Marais, Robert A Hegele, Maurizio R Averna, Cesare R Sirtori, Prediman K Shah, Daniel Gaudet, Claudia Stefanutti, Giovanni B Vigna, Anna Me Du Plessis, Kathleen J Propert, William J Sasiela, Leanne T Bloedon, Daniel J Rader, Davide Noto: Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study.. The Lancet 11/2012;
- C Stefanutti, C Morozzi, G Perrone, S Di Giacomo, A Vivenzio, G D'Alessandri: The lipid- and lipoprotein- [LDL-Lp(a)] apheresis techniques. Updating.. Il Giornale di chirurgia 11/2012; 33(11/12):444-449.
- S Bosi, A Barbieri, M Baldelli, S Censi, M Naldi, A Squeri, C Morozzi, C Stefanutti: How new imaging techniques can aid in defining the cardiovascular profile of the high-risk patient.. Il Giornale di chirurgia 11/2012; 33(11/12):429-434.
- Claudia Stefanutti, Morozzi Claudia, Di Giacomo Serafina: New clinical perspectives of hypolipidemic drug therapy in severe hypercholesterolemia.. Current Medicinal Chemistry 09/2012;
- Claudia Stefanutti, Fabio Mazza: Multiple Lipid-lowering Treatment in Pediatric Patients with Hyperlipidemia.. Medicinal chemistry (Shāriqah (United Arab Emirates)) 07/2012; 8(6):1171-81.
- Cuchel M, Meagher EA, Theron H. du Toit, Blom DJ, Marais AD, Hegele RA, Averna M, Sirtori C, Shah PK, Gaudet D, Stefanutti C, Vigna GB, Du Plessis AME, Kathleen J. Propert, Sasiela WJ, Bloedon LT, Rader DJ: Efficacy and Safety of a Microsomal Triglyceride Transfer Protein Inhibitor in Homozygous Familial Hypercholesterolemia. Lancet. 01/2012;
- Stefanutti Claudia, Morozzi Claudia, Di Giacomo Serafina: Perspectives of hypolipidemic drug therapy in severe hypercholesterolemia. Current Medicinal Chemistry. 01/2012;
- Marina Cuchel, Emma A Meagher, H. du Toit Theron, Dirk Blom, A. D Marais, Robert A Hegele, Maurizio Averna, Cesare Sirtori, Prediman K Shah, Daniel Gaudet, Claudia Stefanutti, Giovanni B Vigna, AME du Plessis, LeAnne T Bloedon, Daniel J Rader, Phase 3 HoFH Lomitapide Study Investigators: Apheresis Treatment does not Affect the Lipid-Lowering Efficacy of Lomitapide, a Microsomal Triglyceride Transfer Protein Inhibitor, in Patients with Homozygous Familial Hypercholesterolemia. Circulation 01/2012; 126:A17396.
- Zenti Maria Grazia, Stefanutti Claudia: Effects of selective H.E.L.P. LDL-apheresis on plasma inflammatory markers concentration in severe dyslipidemia: Implication for anti-inflammatory response.. Cytokine 10/2011; 56(3):850-4.
- Claudia Stefanutti, Antonio Vivenzio, Pietro Manuel Ferraro, Claudia Morozzi, Dany Belotherkovsky: Apheresis-inducible cytokine pattern change in severe, genetic dyslipidemias.. Cytokine 09/2011; 56(3):835-41.
- Claudia Stefanutti, Claudia Morozzi, Andrea Petta: Lipid and low-density-lipoprotein apheresis. Effects on plasma inflammatory profile and on cytokine pattern in patients with severe dyslipidemia.. Cytokine 09/2011; 56(3):842-9.
- C Stefanutti, S Di Giacomo, G Labbadia: Timing clinical events in the treatment of pancreatitis and hypertriglyceridemia with therapeutic plasmapheresis.. Transfusion and Apheresis Science 06/2011; 45(1):3-7.
- C Stefanutti, A Vivenzio, S Di Giacomo, P M Ferraro: Cytokines profile in serum of homozygous familial hypercholesterolemia is changed by LDL-apheresis.. Cytokine 05/2011; 55(2):245-50.
- Stefanutti C, Di Giacomo S, Morozzi C: New evidences of D.A.LI. LDL-apheresis effects on circulating pro- and anti- inflammatory cytokines. Therapeutic Apheresis and Dialysis 01/2011; 15(4):A23-A24:68.
- Stefanutti C, Shafii M, Di Giacomo S, Morozzi C, Mazzilli S: H.E.L.P. LDL-apheresis clinical experience in Italy. Therapeutic Apheresis and Dialysis 01/2011; 15(4):A24:69.
- Stefanutti C: Immunoadsorption apheresis for severe systemic lupus erythematosus with nephritis: a pivotal study. Lupus 01/2011;
- C Stefanutti: The 2009 2nd Italian Consensus Conference on LDL-apheresis.. Nutrition, metabolism, and cardiovascular diseases: NMCD 12/2010; 20(10):761-2.
- Stefanutti, Claudia, Di Giacomo, Serafina: Lipid apheresis in secondary cardiovascular risk prevention in HyperLp(a)lipidemia. Why not?. SciTopics. 03/2010; http://www.scitopics.com/Lipid_apheresis_in_secondary_cardiovascular_ris....
- Claudia Stefanutti: Italian Multicenter Study on Low-Density Lipoprotein Apheresis: retrospective analysis (2007).. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 02/2010; 14(1):79-86.
- Liver Dysfunction Supportive Therapies –From Therapeutic Plasmapheresis toMolecular Adsorbent Recirculating SystemC. Stefanutti1, G. Novelli2, V. Morabito2, S. Di Giacomo1, G. Labbadia1Transplantationsmedizin Organ der Deutschen Transplantationsgesellschaft 4-2010 Editor-in-Chief: Indikation und Effekt der Plas- mapherese bei Nierentransplan- tierten Nierentransplantation bei hoch- immunisierten Patienten -Stel- lenwert der Plasmapherese Klinische Pfade als Mittel zum Prozessmanagement in der Ni. Transplantationsmedizin. 01/2010;
- Stefanutti C, Novelli G, Morabito V, S. Di Giacomo, Labbadia G: Liver Dysfunction Supportive Therapies - From Therapeutic Plasmapheresis to Molecular Adsorbent Recirculating System. Transplantationsmedizin. 01/2010;
- C Stefanutti, G D'Alessandri, G Russi, G De Silvestro, M G Zenti, P Marson, D Belotherkovsky, A Vivenzio, S Di Giacomo: Treatment of symptomatic HyperLp(a)lipoproteinemia with LDL-apheresis: a multicentre study.. Atherosclerosis. Supplements 12/2009; 10(5):89-94.
- Pasquale Pignatelli, Roberto Carnevale, Roberto Cangemi, Lorenzo Loffredo, Valerio Sanguigni, Claudia Stefanutti, Stefania Basili, Francesco Violi: Atorvastatin inhibits gp91phox circulating levels in patients with hypercholesterolemia.. Arteriosclerosis Thrombosis and Vascular Biology 12/2009; 30(2):360-7.
- Claudia Stefanutti, Serafina Di Giacomo, Antonio Vivenzio, Giancarlo Labbadia, Fabio Mazza, Giovanna D'Alessandri, Giampaolo Russi, Giustina De Silvestro, Piero Marson: Therapeutic plasma exchange in patients with severe hypertriglyceridemia: a multicenter study.. Artificial Organs 12/2009; 33(12):1096-102.
- C Stefanutti, A Vivenzio, S Di Giacomo, B Mazzarella, P M Ferraro, S Abbolito: Treatment of symptomatic hyperLp(a)lipidemia with LDL-apheresis vs. usual care.. Transfusion and Apheresis Science 11/2009; 42(1):21-6.
- Claudia Stefanutti, Serafina Di Giacomo, Bruno Mazzarella, Alessandro Castelli: LDL apheresis: a novel technique (LIPOCOLLECT 200).. Artificial Organs 11/2009; 33(12):1103-8.
- Claudia Stefanutti, Antonio Vivenzio, Serafina Di Giacomo, Giancarlo Labbadia, Fabio Mazza, Giovanna D'Alessandri, Pietro M Ferraro, Cesare Masala: Immunoadsorption apheresis and immunosuppressive drug therapy in the treatment of complicated HCV-related cryoglobulinemia.. Journal of Clinical Apheresis 11/2009; 24(6):241-6.
- Claudia Stefanutti, Fabio Mazza, Antonio Vivenzio, Serafina Di Giacomo, Giuseppina Perrone, Mariarosaria Serra, Antonello Bucci: Combined treatment with Dif1stat and diet reduce plasma lipid indicators of moderate hypercholesterolemia more effectively than diet alone: a randomized trial in parallel groups.. Lipids 11/2009; 44(12):1141-8.
- Claudia Stefanutti: Clinical trials in apheresis.. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 07/2009; 13(3):171-3.
- Claudia Stefanutti, Antonio Vivenzio, Serafina Di Giacomo, Bruno Mazzarella, Giovanna Bosco, Andrea Berni: Aorta and coronary angiographic follow-up of children with severe hypercholesterolemia treated with low-density lipoprotein apheresis.. Transfusion 04/2009; 49(7):1461-70.
- Giustina De Silvestro, Tiziana Tison, Maria Vicarioto, Paola Bagatella, Claudia Stefanutti, Piero Marson: The Italian Registry of Pediatric Therapeutic Apheresis: a report on activity during 2005.. Journal of Clinical Apheresis 01/2009; 24(1):1-5.
- Fabio Mazza, Claudia Stefanutti, Serafina Di Giacomo, Antonio Vivenzio, Nadia Fraone, Bruno Mazzarella, Antonello Bucci: Effects of low-dose atorvastatin and rosuvastatin on plasma lipid profiles: a long-term, randomized, open-label study in patients with primary hypercholesterolemia.. American Journal of Cardiovascular Drugs 01/2008; 8(4):265-70.
- E Bravo, M Napolitano, I Lopez-Soldado, M Valeri, K M Botham, C Stefanutti: Hypercholesterolaemia alters the responses of the plasma lipid profile and inflammatory markers to supplementation of the diet with n-3 polyunsaturated fatty acids from fish oil.. European Journal of Clinical Investigation 12/2006; 36(11):788-95.
- E. Bravo, M. Napolitano, I. Lopez, K. M. Botham, C. Stefanutti: We-P14:461 Dietary fish oil alters the plasma lipid profile and the expression of HNF4alpha in hypercholesterolemic rats. Atherosclerosis Supplements - ATHEROSCLER SUPPL. 01/2006; 7(3):448-448.
- Claudia Stefanutti, Antonio Vivenzio, Serafina Di Giacomo, Maura Mareri, Fulvia Ceccarelli, Guido Valesini: Cyclophosphamide and immunoadsorption apheresis treatment of lupus nephritis nonresponsive to drug therapy alone.. BioDrugs 02/2005; 19(2):129-33.
- C Stefanutti, A Lanti, S Di Giacomo, M Mareri, F De Lorenzo, A Landolfo, G Isacchi: Therapeutic apheresis in low weight patients: technical feasibility, tolerance, compliance, and risks.. Transfusion and Apheresis Science 09/2004; 31(1):3-10.
- Stefano Bertolini, Livia Pisciotta, Lilla Di Scala, Silvia Langheim, Antonella Bellocchio, Paola Masturzo, Alfredo Cantafora, Scipione Martini, Maurizio Averna, Gianni Pes, Claudia Stefanutti, Sebastiano Calandra: Genetic polymorphisms affecting the phenotypic expression of familial hypercholesterolemia.. Atherosclerosis 06/2004; 174(1):57-65.
- C Stefanutti, A Bucci, S Di Giacomo, N Fraone, A Pace, M Mareri, A Musca, A Mammarella: Efficacy, safety and tolerability of combined low-dose simvastatin-fenofibrate treatment in primary mixed hyperlipidaemia.. Clinical Drug Investigation 02/2004; 24(8):465-77.
- P Marson, G Zanchin, C Stefanutti: [Some historical considerations on the inflammatory theory of atherosclerosis].. Reumatismo 01/2004; 56(3):215-9.
- C Stefanutti, S Di Giacomo, M Mareri, F De Lorenzo, G D'Alessandri, F Angelico, A Bucci, A Musca, A Mammarella: Immunoadsorption apheresis (Selesorb) in the treatment of chronic hepatitis C virus-related type 2 mixed cryoglobulinemia.. Transfusion and Apheresis Science 07/2003; 28(3):207-14.
- C Stefanutti, S Di Giacomo, M Di Caro, A Vivenzio, A Musca: DALI low-density lipoprotein apheresis in homozygous and heterozygous familial hypercholesterolemic patients using low-dose citrate anticoagulation.. Therapeutic Apheresis and Dialysis 11/2001; 5(5):364-71.
- C Stefanutti, S Di Giacomo, A Vivenzio, V Colloridi, G Bosco, A Berni, I Rabbone, F Cerutti, S Bertolini: Low-density lipoprotein apheresis in a patient aged 3.5 years.. Acta Paediatrica 07/2001; 90(6):694-701.
- C Stefanutti, S Di Giacomo, A Vivenzio, G C Isacchi, R Masella, P Caprari, R Varì, A Tarzia, A Mosiello, A Cantafora: Acute and long-term effects of low-density lipoprotein (LDL)-apheresis on oxidative damage to LDL and reducing capacity of erythrocytes in patients with severe familial hypercholesterolaemia.. Clinical Science 02/2001; 100(2):191-8.
- Claudia Stefanutti: La LDL-aferesi: Stato attuale. La Clinica terapeutica 01/2001; 152(1):65-69.
- Stefano Bertolini, Alfredo Cantafora, Maurizio Averna, Claudio Cortese, Corradino Motti, S. Martini, Giovanni Mario Pes, Alfredo Postiglione, Claudio Stefanutti, Ida Blotta, Livia Pisciotta, Marina Rolleri, Silvia Langheim, Margherita Ghisellini, Ivana Rabbone, Sebastiano Calandra Buonaura: Clinical expression of familial hypercholesterolemia in clusters of mutations of the LDL receptor gene that cause a receptor-defective or receptor-negative phenotype. Arteriosclerosis Thrombosis and Vascular Biology 10/2000;
- C Stefanutti, G Lucani, A Vivenzio, S Di Giacomo: Diet only and diet plus simvastatin in the treatment of heterozygous familial hypercholesterolemia in childhood.. Drugs under experimental and clinical research 02/1999; 25(1):23-8.
- C Stefanutti, G Lucani, A Vivenzio, S Di Giacomo, E Lucani, B Mazzarella: Pattern of red blood cells and platelets cholesterol and fatty acids in homozygous familial hypercholesterolemic patients treated with LDL-apheresis.. La Clinica terapeutica 01/1998; 149(3):231-3.
- C Stefanutti, A Vivenzio, G Lucani, S Di Giacomo, E Lucani: Effect of L-carnitine on plasma lipoprotein fatty acids pattern in patients with primary hyperlipoproteinemia.. La Clinica terapeutica 01/1998; 149(2):115-9.
- C Stefanutti, A Notarbartolo, V Colloridi, A Nigri, A Vivenzio, S Bertolini, G Bosco, A Berni, S Di Giacomo, B Mazzarella: LDL apheresis in a homozygous familial hypercholesterolemic child aged 4.5.. Artificial Organs 11/1997; 21(10):1126-7.
- Stefanutti C, Vivenzio A, Di Giacomo S: Lipid Clinic - La scheda: Laboratorio di Plasmaferesi Terapeutica dell’Istituto di Terapia Medica Sistematica, Universita’ degli Studi di Roma “La Sapienza” - Policlinico Umberto I. Arteriosclerosi News ISSN 1123 - 1378. 09/1997; Year 4, 3(Sett-Dic. 1997):12.
- Claudia Stefanutti, Berni A, Abbolito S, Di Giacomo S, Di Luozzo M, Vivenzio A, Papalia U, Nigri A: Progressione-Regressione di lesioni coronariche in pazienti con ipercolesterolemia sottoposti a plasmaferesi. Giornale italiano di cardiologia 06/1997; 27(1):12 C38.
- Bianciardi, Tanganelli, DeSanti, MM, Stefanutti C: Ultrastructural morphometry of leukocytes and platelets in familial hypercholesterolemic patients subjected to LDL-apheresis. Atherosclerosis 01/1997; 133(2):11.
- Stefanutti C, Di Giacomo S, Vivenzio A: Comparison between different techniques of LDL-apheresis. The International journal of artificial organs 01/1997; 21((S-6)):66-71.
- Bianciardi G, Stefanutti C, Carducci A, Mazzarella B, Di Giacomo S, Vivenzio A, Tanganelli P, Alessandri C, Weber G, Ricci G: Platelet activation in hypercholesterolemic patients submitted to therapeutic plasmapheresis. An ultrastructural study.. Hematology 01/1997; 2: 491- 496.
- C. Stefanutti, S. Di Giacomo, A. Vivenzio, G. Bosco, V. Colloridi, S. Trizza, A. Berni, A. Nigri, N. Koga: 4.P.412 LDL-apheresis in the treatment of familial hypercholesterolemia in childhood. Atherosclerosis 01/1997; 134(1):383-384.
- C. Stefanutti, S. Di Giacomo, A. Vivenzio, G. Bosco, V. Colloridi, A. Bucci: 4.P.411 Diet only and diet plus simvastatin in the treatment of heterozygous familial hypercholesterolemia in childhood. Atherosclerosis 01/1997; 134(1):383-383.
- Urbinati, GC, Angelico, Barbato, Stefanutti C: The ''Gradoli project'': Genetic epidemiology applied to the study of familial hypercholesterolemia. Atherosclerosis 01/1997; 133(2):54.
- Antonini, Giubilei, Mazzarella, Stefanutti C: Apolipoprotein E (Apo E) phenotype and genotype in ischemic cerebrovascular disease (S), Alzheimer disease (AD) and in multi-infarctual dementia (MID). Atherosclerosis 01/1997; 133(2):2.
- C Stefanutti, A Vivenzio, S Di Giacomo, C Colombo, B Mazzarella, M Fontana, G Ricci: A new treatment of refractory ascites: ascitoapheresis.. Journal of Clinical Apheresis 02/1996; 11(1):46-7.
- G Perrone, C Stefanutti, P Galoppi, G Anelli, O Capri, G Lucani, A Vivenzio, B Mazzarella, L Zichella: Effect of oral and transdermal hormone replacement therapy on lipid profile and Lp(a) level in menopausal women with hypercholesterolemia.. International journal of fertility and menopausal studies 01/1996; 41(6):509-15.
- Bosco G, Ventriglia F, Stefanutti C, Borzaga U, Belardi C, Colloridi V: L’ipercolesterolemia familiare omozigote: efficacia della plasmaferesi nella prevenzione e possibile risoluzione delle alterazioni coronariche. Rivista italiana di pediatria = The Italian journal of pediatrics 01/1996; 22(5-2):87.
- Perrone G, Stefanutti C, Galoppi P, Anelli G, Capri O, Lucani G.C, Vivenzio A: Effect of oral and transdermal hormonal replacement therapy on lipid profile and Lp (a) level in menopausal women with hypercholesterolemia. Int. J. Fertility Women’s Med. 01/1996; 41(6):509-515.
- C Stefanutti, A Vivenzio, C Colombo, S Di Giacomo, B Mazzarella, A Berni, A Nigri, N Koga: Treatment of homozygous and double heterozygous familial hypercholesterolemic children with LDL-apheresis.. The International journal of artificial organs 03/1995; 18(2):103-10.
- S Bertolini, R Garuti, W Lelli, M Rolleri, R M Tiozzo, M Ghisellini, M L Simone, P Masturzo, N C Elicio, C Stefanutti: Four novel partial deletions of LDL-receptor gene in Italian patients with familial hypercholesterolemia.. Arteriosclerosis Thrombosis and Vascular Biology 02/1995; 15(1):81-8.
- C Stefanutti, A Vivenzio, C Colombo, S Di Giacomo, B Mazzarella, A Berni, A Nigri, N Koga: LDL-apheresis in pediatric patients with severe hyperlipoproteinemia.. Journal of Clinical Apheresis 02/1995; 10(2):101-2.
- A. Menditto, F. Chiodo, S. Giampaoli, A. Menotti, G. Ricci, G.C. Urbinati, F. Angelico, M. Arca, A. Bucci, A.M. Buongiorno, D. Consalvi, R. Conti, G. Dangelo, A. Defilippis, M. Delben, E. Delmonaco, S. Fazio, A. Montali, F. Pannozzo, A. Pontecorvi, P. Ricci, L. Sibilia, G.L. Sotis, C. Stefanutti, R. Volpe, S. Barzotti, M. Capelli, R. Capocaccia, G. Dicarlo, F. Dima, C. Lonoce, P. Lombari, M. Pasquali, A. Santaquilani, A. Verdecchia, G. Morisi: Association of Serum Selenium with Selected Cardiovascular Risk Factors. Microchemical Journal 02/1995; 51(s 1–2):170–180.
- N. Lelli, R. Garuti, P. Pedrazzi, M. Ghisellini, M. L. Simone, R. Tiozzo, L. Cattin, M. Valenti, M. Rolleri, S. Bertolini, C. Stefanutti, S. Calandra: A new missense mutation (Cys297→Phe) of the low density lipoprotein receptor in Italian patients with familial hypercholesterolemia (FHTrieste). Human Genetics 01/1994; 93(5):538-540.
- C. Stefanutti, A. Vivenzio, G. Lucani, S. Di Giacomo, C. Colombo, M.A. Bianchi, G. Ricci: Simvastatin and pravastatin: A daily dose of 40 mg in the long-term treatment of primary hypercholesterolemia. Current Therapeutic Research. 01/1994;
- C Stefanutti, A Vivenzio: [First prenatal diagnosis of familial hypercholesterolemia by a molecular biology technic].. La Clinica terapeutica 09/1993; 143(2):99-103.
- Domenico A. Coviello, Stefano Bertolini, Paola Masturzo, Margherita Ghisellini, Roberta Tiozzo, Franca Zambelli, Claudia Stefanutti, Francesco Torcia, Antonio Pachi, Giorgio Ricci, Sebastiano Calandra: Chorionic DNA analysis for the prenatal diagnosis of familial hypercholesterolaemia. Human Genetics 01/1993; 92(4):424-426.
- Claudia Stefanutti, Antonio Vivenzio, Serafina Di Giacomo: La LDL-aferesi: indicazioni terapeutiche. Metabolismo Oggi. 01/1993; 10(2):44-54.
- Stefanutti C, Vivenzio A, Di Giacomo S, Colombo C, Alessandri C, Ricci G: Plasma Lp(a) profile in patients with familial hypercholesterolemia treated by dextransulfate cellulose LDL-apheresis and plasma-exchange.. Therapeutic apheresis and dialysis: official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 01/1992;
- Claudia Stefanutti, Giovanna Bosco, E Giglioni, D Di Vito, V Bastianon, Vincenzo Colloridi: Le ipercolesterolemie mono e poligeniche in età pediatrica: risultati preliminari di uno studio clinico-terapeutico. Giornale italiano di Cardiologia. 09/1991; 21(Suppl 2):7 C17.
- A Cristin, D Gasparini, S Pappalardo, C Stefanutti, F Aveni: [Isolated jejunal angiomatosis. A rare cause of intestinal hemorrhage].. Minerva chirurgica 01/1991; 45(23-24):1477-9.
- Stefanutti C, Perrone G, Galoppi P, Mancone M, Capri O, Valente M: Different Hormonal Treatment In Pre- and Post-Menopausal Women: Effect on theCardiovascular Risk. Gynecological Endocrinology 01/1989; 3(Suppl. 1-242):212..
- Attili A. F, Lalloni L, Stefanutti C, GREPCO: Natural history of gallstones (GS). A four to six year follow-up study of asymptomatic and symptomatic patients. Gastroenterology 01/1989;
- Spagnolo A, Menotti A, Giampaoli S, Morisi G, Buongiorno A, Urbinati G.C, Righetti G, Ricci G, Stefanutti C, the members of 6 Research Groups: High density lipoprotein cholesterol distribution and predictive power in some italian populations studies. European Journal of Epidemiology 01/1989; 0392-2990, 5:328-335.
- Angelico F, Del Ben M, Stefanutti C, GREPCO: Obesity as a risk factor for gallstone disease: results of a six-years follow-up study. International Journal of Obesity 01/1989; 13 (suppl.1):24.
- Angelico F, Stefanutti C, GREPCO: Risk factors for gallstone disease in the GREPCO studies. Gastroenterology 01/1989;
- C Stefanutti, G C Isacchi, R Antonini, A Bucci, A Cardillo, G D Di Nucci, M Gozzer, F Malagnino, M Masci, B Mazzarella: Selective continuous removal of low density lipoproteins by dextran sulfate cellulose column adsorption apheresis in the therapy of familial hypercholesterolemia.. Beiträge zur Infusionstherapie = Contributions to infusion therapy 02/1988; 23:172-82.
- Claudia Stefanutti, Gruppo di Ricerca del Progetto DiSCo, Urbinati GC, Menotti A, Giampaoli S, Arca M: Il Progetto Distretto Sezze Controllo Comunitario delle malattie cronico-degenerative (Di.S.Co.): dati relativi all'esame iniziale. ISTISAN. 01/1988; ISSN 0391-1675(88/6):1-161.
- Claudia Stefanutti, et al: Prevenzione e trattamento degli squilibri nutrizionali cronici nell’anziano. Alim. Nutr. Metabol. 01/1987; 8(3):203-224.
- Claudia Stefanutti: Prevalenza e distribuzione geografica della litiasi biliare. Progressi Clinici: Medicina. 01/1987; 2(5):205-219.
- the DISCO, GREPCO, Stefanutti C: Epidemiology of gallstone disease in Italy: comparison between a rural and urban female population. It. J. Gastroenterol. 01/1987;
- the DISCO, GREPCO, Stefanutti C: Epidemiology of gallstone disease in Italy: comparison between a rural and urban female population. The Italian Journal of Gastroenterology. 01/1987; 19:129-133.
- Arca M, Stefanutti C, GREPCO: Erithrocyte fatty acid composition and gallstone disease: results and epidemiological survey. American Journal of Clinical Nutrition 01/1987; 46:110-114.
- V Fanelli, F Angelico, C Stefanutti, A Calvieri, S Fazio: [Effects of the integration of a habitual diet with glucomannan fiber in hypercholesterolemia. A clinical study in familial and sporadic hyperlipoproteinemia with lipo-proteic phenotype IIa and IIb].. La Clinica terapeutica 11/1986; 119(1):17-23.
- Claudia Stefanutti, Bollea MR, Cairella M, Fabbrizzi MP, Fabiani L, Nasta G, Pretaroli AR, Riganelli S, Sacchetti Gi, Zanni AM: Folate deficiency in the elderly. Preliminary observations. Clinica Dietologica. 05/1986; 13(3):193-194.
- Claudia Stefanutti, Cairella M., Calvitti A., Fabbrizzi M.P., Fabiani L., Formicuccia P., Marino G., Nasta G., Pretaroli A.R., Riganelli S, Zanni A.M.: Overweight and obesity in elderly. Clin Dietol. 01/1986; 13(3):195-196.
- Fanelli V, Angelico F, Stefanutti C, Calvieri A, Fazio S: Effetti della integrazione della dieta abituale con le fibre di glucomannano nelleiperliproteinemie familiari e sporadiche con fenotipo lipoproteico IIa e IIb. La Clinica terapeutica 01/1986; 119(1):17-23.
- Knuiman J.T, Hautvast J.G.A.J, Van Der Heyden L, Geboers J, Joossens J.V, Tornqvist H, Isaksson B, Pitinen P, Tuomiletho J, Poulsen L, Flynn A, Shortt C, Boing H, Yomtov B, Magalhaes E, Angelico F, Stefanutti C, Fazio S, Cantini R, Ricci G, Trichopoulou A, Katapoti Z: A multi-centre study on completeness of urine collection in 11 European Centre. I.. Human nutrition. Clinical nutrition 01/1986; 40C:229-237.
- Capocaccia L, Ricci G, Stefanutti C, the Rome Group for Epidemiology and: Prevention of Cholelithiasis (GREPCO) (1985):Epidemiology of gallstone disease.. The Italian Journal of Gastroenterology. 01/1985; 17:215-218.
- the Rome Group for Epidemiology, Prevention of Cholelithiasis, Stefanutti C: Prevalence of cholelithiasis in a female population and study of risk factors sex-related. Italian journal of gastroenterology and hepatology 01/1984;
- Claudia Stefanutti: Prevalence of gallstone disease in an Italian adult female population. American Journal of Epidemiology 01/1984; 119(5):796-805.
- Claudia Stefanutti, Anna Montali, Sergio Fazio, Marcello Arca, Stefania Ciocca: Is there an association between diet and cholelithiasis? Effect of nutritional factors and dietary behaviour on bile lithogenecity. Epatologia 11/1983; 29(6(161)):253-280.
- Claudia Stefanutti, Francesco Angelico: Asymptomatic cholelithiasis:myth or reality? Natural evolution, medical therapy and "prophilactic" cholecystectomy. Epatologia 05/1983; 29(3(158)):121-129.
- Claudia Stefanutti, Francesco Angelico: Coincidence of gallbladder disease and coronary heart disease: critical review of the literature. Epatologia 11/1982; 28(6,155):365-376.
- Angelico F., Arca M., Buongiorno A., Calvieri A., Monini P., Morisi G., Ricci G., Stefanutti C: Serum high density lipoprotein cholesterol in an Italian adult population sample: correlation with the main coronary risk factors. Clinica & Terapia Cardiovascolare. 01/1982; 1(3):187-192.
- C Stefanutti, A Vivenzio, G Lucani, S Di Giacomo: [LDL-apheresis: current status].. La Clinica terapeutica 152(1):65-9.
- S Passalacqua, E Staffolani, F Aureli, P M Ferraro, Malattie Dismetaboliche, Anedda Sandra, G Brotzu, Stefanutti Claudia, La Sapienza, Roma et al.
- Claudia Stefanutti, Serafina Di Giacomo, Claudia Morozzi: [LDL apheresis: an update and overview. LDL apheresis in Sardinia, Italy (SMILDLa)].. Giornale italiano di nefrologia: organo ufficiale della Societa italiana di nefrologia 29 Suppl 54:S14-8.
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- Conference Proceedings
- Claudia Stefanutti, M. Cuchel, D.J. Blom, M. Averna, E.A. Meagher, H. Du T. Theron, C.R. Sirtori, R.A. Hegele, P.K. Shah, D. Gaudet, G. Vigna, L.T. Bloedon, D.J. Rader, the AEGR-012 Study Investigators: Elevations in Hepatic Fat appear to be Stable in Patients with Homozygous Familial Hypercholesterolemia Treated with the Microsomal Triglyceride Transfer Protein Inhibitor, Lomitapide: Results of an Ongoing Long-Term Extension Study. American Heart Association, Dallas, Texas, USA; 11/2013
- Marina Cuchel, Dirk J Blom, Maurizio R Averna, Emma A Meagher, Hendrik du Toit Theron, Cesare R Sirtori, Robert A Hegele, Prediman K Shah, Daniel Gaudet, Claudia Stefanutti, Giovanni B Vigna, LeAnne T Bloedon, Daniel J Rader, the HoFH lomitapide study investigators: [techrep.title].
- Claudia Stefanutti, C. Sirtori, M. Cuchel, E.A. Meagher, H. Du T. Theron, D.J. Blom, M. Averna, R.A. Hegele, P.K. Shah, D. Gaudet, G. Vigna, A.M.E. Du Plessis, L.T. Bloedon, D.J. Rader on Behalf of the AEGR-012 Study Investigators: Sustained LDL-C Lowering in Patients with Homozygous Familial Hypercholesterolemia treated with Lomitapide for 2.5 years: Results of a Long-Term Extension Study. European Society of Cardiology, Amsterdam, Netherlands; 08/2013
- M Cuchel, EA Meagher, H dT Theron, DJ Blom, AD Marais, RA Hegele, MR Averna, CR Sirtori, PK Shah, D Gaudet, AME du Plessis, LT Bloedon, DJ Rader, C Stefanutti: [techrep.title].
- Claudia Stefanutti, M Cuchel, EA Meagher, H dT Theron, DJ Blom, AD Marais, RA Hegele, MR Averna, CR Sirtori, PK Shah, D Gaudet, GB Vigna, AME du Plessis, LeAnne T Bloedon, Daniel J Rader, Phase 3 HoFH Lomitapide Study Investigators: Treatment of Homozygous Familial Hypercholesterolemia with the Treatment of Homozygous Familial Hypercholesterolemia with the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide. The World Congress of Clinical Lipidology, Budapest, Hungary; 12/2012
- C Stefanutti, M Cuchel, Ea Meagher, H Dt Theron, Dj Blom, Ad Marais, Ra Hegele, Mr Averna, Cr Sirtori, Pk Shah, D Gaudet, Gb Vigna, Ame Du Plessis, Leanne T Bloedon, Daniel J Rader: [techrep.title].
- Claudia Stefanutti, Andrea Petta, Claudia Morozzi: EFFECTS OF LDL-APHERESIS ON PLASMA INFLAMMATORY PROFILE AND ON CYTOKINE PATTERN IN PATIENTS WITH SEVERE DYSLIPIDEMIA. 80 Th European Atherosclerosis Society Congress; 05/2012
- L. Pisciotta, C. Stefanutti, M. Gozzer, C. Morozzi, G. Bosco: [techrep.title].
- Claudia Stefanutti: Treatment of symptomatic HyperLp(a)lipoproteinemia with LDL-apheresis: a multicenter study. The 15th Annual Meeting Of The Israeli Society For Research, Prevention And Treatment Of Atherosclerosis Eilat, Israel, October 14-17 2010; 10/2010
- Claudia Stefanutti: [techrep.title].
- Claudia Stefanutti: A novel DALI LDL-apheresis system using low-dose citrate anticoagulation. Joint Congress of the XIII European Society for Haemapheresis & X Congresso della Società Italiana di Emaferesi, Riva del Garda, Trento, Italy; 09/2001
- Claudia Stefanutti: [techrep.title].
- Claudia Stefanutti, Di Giacomo S, Di Caro M, Vivenzio A, Musca A: Immunoadsorption Apheresis: Clinical Evaluation of Two Systems. Joint Congress of the XIII European Society for Haemapheresis & X Congresso della Società Italiana di Emaferesi, Riva del Garda, Trento, Italy; 09/2001
- Stefanutti C, Vivenzio A, Di Giacomo S, Mazzarella B: [techrep.title].
- Claudia Stefanutti, Di Giacomo, A . Vivenzio, G . Bosco, V. Colloridi, S. Trizza, A. Berni, A. Nigri, N. Koga: LDL-apheresis in the treatment of familial hypercholesterolemia in childhood. 11th International Symposium on Atherosclerosis, Paris, October 1997; 10/1997
- Claudia Stefanutti, S . Di Giacomo, A . Vivenzio, G . Bosco, V. Colloridil: [techrep.title].
- Claudia Stefanutti: Pediatric LDL-apheresis: clinical experience in Italy's largest sample. Current Trends of the Prevention of Atherosclerosis in Childhood. 2 Eds Tamas Szamosi; 01/1997
- Claudia Stefanutti, Vivenzio A, Di Giacomo S, Mazzarella B, Ricci G: [techrep.title].
- Claudia Stefanutti, Vivenzio A, Di Giacomo S, Mazzarella B, Urbinati GC: Plasmapheresis in the treatment of Primary Hyperlipoproteinemia with Hyperchylomicronemia. World Apheresis Association 6th International Congress, Firenze, Italia; 11/1996
- Stefanutti C, Mazzarella B, Di Giacomo S, Vivenzio A: [techrep.title].
- Stefanutti C., Vivenzio A., Di Giacomo S., Colombo C., Ferrazzoli I., Ricci G.: LDL-aferesi: indicazioni alle diverse metodiche. SIdE. VII Congresso Nazionale. Napoli, 16-19 Maggio, 1995; 05/1995
- Stefanutti C., Vivenzio A., Di Giacomo S., Lucani G.C., Colombo C: [techrep.title].
- Stefanutti C., Vivenzio A., Di Giacomo S., Mazzarella B., Lucani G., Colombo C.: Oltre 3 e 5 anni di trattamento dell’ipercolesterolemia familiare omozigote mediante plasmaferesi terapeutica. VI Congresso Nazionale della Società Italiana di Emaferesi - Montesilvano Lido (PE), Italia, 1-4 Giugno 1993; 06/1993
- Claudia Stefanutti: [techrep.title].
- Claudia Stefanutti: Long-term treatment of homozygous familial hypercholesterolaemia with selective and conventional plasmapheresis. 4th International Congress of the World Apheresis Association and the 12th Annual Symposium of the Japanese Society for Apheresis; 06/1992
- Claudia Stefanutti, A. Russo, R. Pretagostini, A. Lopez, M. G. Quaglia: [techrep.title].
- Zichella L., Perrone G., Stefanutti C., Capri O., Galoppi P., Barillaro F., Bianchi A.M.: Hormonal replacement therapy in hypercholesterolemic women. Menopause Update 1992; 05/1992
- Claudia Stefanutti, Vivenzio A., Di Giacomo S., D’Angelo S, Cerratti L., Mazzarella B., Ricci G.: [techrep.title].
- Claudia Stefanutti, Vivenzio A., Bruni P., Cerratti L., Antonini R., Ricci G: Il trattamento extracorporeo mediante plasmaferesi della Sindrome di Raynaud: un caso clinico. Società Italiana di Emaferesi. V Congresso Nazionale Salice Terme (PV); 05/1991
- Claudia Stefanutti, Vivenzio A., Mazzarella B., Masci M., Cardillo A., Gozzer M., Isacchi G.C., Ricci G: [techrep.title].
- Zichella L., Perrone G., Capri O., Galoppi P., Anelli G., Stefanutti C., Ricci G: Valutazione degli effetti dell’estrogenoterapia sul profilo plasmatico dei lipidi e delle lipoproteine in donne normocolesterolemiche ed ipercolesterolemiche. LXVIII Congresso della Societa’ Italiana di Ginecologia ed Ostetricia - XXXIII Congresso A.O.G.O.I.; 01/1991
- Claudia Stefanutti, Isacchi GC, Mazzarella B, Vivenzio A, Masci M, Gozzer M, Ricci G: [techrep.title].
- Claudia Stefanutti, Giuseppina Perrone, Oriana Capri, Paola Galoppi, Antonio Vivenzio, Paolo Venditti, Giuseppe Anelli, Lucio Zichella: Iperlipoproteinemia e rischio di osteoporosi:studio clinico su un gruppo di pazienti ambulatoriali in età perimenopausale. LXVII Congresso Nazionale della Società Italiana di Ginecologia e Ostetricia; 09/1990
- Claudia Stefanutti, Urbinati G.C, Research Group of the Di.S.Co. Project: [techrep.title].
- Claudia Stefanutti, Giuseppina Perrone, Mara Mancone, Paolo Pietrobattista, P Matelassi, Lucio Zichella: Utilizzazione di un contraccettivo orale contenente 20 mcg di etinilestradiolo e 150 mcg di desogestrel in un gruppo di donne in premenopausa: effetti sul rischio cardiovascolare. 3°Congresso della Società Italiana per la Menopausa, Bologna; 11/1988
- Claudia Stefanutti, Elisabetta Tesseri, Giuseppina Perrone, A Camilli, Paola Galoppi, Bruno Mazzarella, A Masci, P Avitto, Antonio Rocco, Lucio Zichella: [techrep.title].
- Tesseri E, Zichella L, Ciocca S, Mancone M, Masala L, Perrone G, Rocco A, Urbinati GC, Stefanutti Claudia: La malattia aterosclerotica e la menopausa: relazioni tra gli steroidi sessuali i lipidi, le lipoproteine e le apolipoproteine plasmatiche. Terza Età della Donna "Prevenzione e Terapia in Climaterio", Rome, Italy; 04/1987
- Claudia Stefanutti, Giancarlo Urbinati, Giuseppina Perrone, M Pasquali, The Di.S.Co. Group: [techrep.title].
- Claudia Stefanutti, Mancone M., Perrone G., Tesseri E., Masci A., Sorbello M., Zucca A., Fabiani L., Zichella L: Pattern sintomatologico, peso corporeo ed abitudini di vita in un gruppo di donne in peri- e post-menopausa. Satellite Symposium to the Fifth International Congress on the Menopause, Roma, Italy; 04/1987
- Claudia Stefanutti, Bucci A, Conti R, Azzarri L, Del Monaco E, Fiermonte GC, Lalloni L, Menotti A, Pasquali M, Ricci P, Scarno AG, Sotis GL, Triozzi M, Urbinati GC, Ricci G: [techrep.title].
- Claudia Stefanutti, Livio Capocaccia: Epidemiology of gallstone disease. 42nd Falk Symposium - VIIIth International Bile Acid Meeting, Berne, Switzerland; 08/1984
- Claudia Stefanutti, Giancarlo Urbinati, The GREPCO Group: [techrep.title].
- Claudia Stefanutti, Francesco Angelico, The GREPCO Group: Factors associated with gallstone disease: observations in the GREPCO study. International Workshop on the Epidemiology and Prevention of Gallstone Disease, Rome, Italy; 12/1983
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- Publications: 238 (not all reported; see also PubMed, Scopus, ISI Web of Knowledge)

- Impact points: 365.29

- Citations: 1.163

Rome, May 2, 2016 Claudia Stefanutti