ANDREA ISIDORI

I - EDUCATION
University graduation : 1999 - Sapienza University of Rome Degree in Medicine 110/110 e lode
Post-graduate studies: 2000-2002 - St. Bartholomew’s Hospital – Queen Mary University of London Honorary Clinical Assistant - Research Fellow Prof. Besser and Prof. Grossman
PhD Graduation: 2004-2008 - PhD in Scienze e Teconologie Cellulari – Dipt. Istologia ed Embriologia Generale Sapienza University Prof. Stefanini
Specialty : 1999-2004 - Endocrinologia e Malattie del Ricambio – Dipartimento di Fisiopatologia Medica – Sapienza University Degree 70/70 e lode
Licensure 02 1999 Ordine dei Medici di Roma Full Registration # M50039
Licensure 01 2000 General Medical Council of London Full Registration # 4747275

II – ACADEMIC APPOINTMENTS
2000-2001 : St. Bartholomew’s Hospital – London UK Honorary Clinical Assistant – Prof. Besser
2001-2002 : Queen Mary University of London Research Fellow – Prof. Grossman
03/2008 - 09/2015 : Sapienza University of Rome Ricercatore a Tempo Indeterminato (Assistant Professor)
Since 02/2014 : ANVUR (Abilitazione Scientifica Nazionale, prima tornata 2012) Abilitazione II Fascia con superamento di 3/3 mediane richieste per il settore SSD 06/D2.
Since 10/2015 : Sapienza University of Rome Professore Associato (Associate Professor)
Since 04/2017 : ANVUR (Abilitazione Scientifica Nazionale, bando D.D. 1532/2016) Abilitazione I Fascia con superamento di 3/3 mediane richieste per il settore SSD 06/D2.

III – RESEARCH APPOINTMENTS
1998-1998 : National Institute of Child health Disease (NICHD), NIH Bethesda, USA Dr ML Dufau Summer Student in preparation of his Experimental MD thesis
2007-2007 : Endocrine Oncology and Molecular Endocrinology – London, UK - Prof. Korbonits - Prof A Clarke 12 months - SIE Exchange research grant for studies on AMPKinase in adipose tissue
2012-2013 : AIFA Advisor for EMA co-rapporteur on a PDE5 inhibitor
2012-2014 : SIAMS – Società Italiana di Andrologia e Medicina della Sessualità Member of Executive Committee
2013-2015 : Journal of Endocrinological Investigations Editorial Board
2014-2015 : SIE – Società Italiana di Endocrinologia Member of Scientific Committee
2014-2015 : ISSM – International Society for Sexual Medicine Appointed for the International Consultation of Sexual Medicine – Madrid 2015
2014-2018 : EAA – European Academy of Andrology Member of Executive Committee (elected during the ECA 2014 Barcelona meeting)
2018-2022 : EAA – European Academy of Andrology Re-elected member of the Executive Committee (elected for a second turn during the ICA 2018 Budapest meeting)
2017-2021 : ISA – International Society of Andrology Elected Treasurer of ISA (elected during the ICA 2017 Copenhagen meeting)
2015-2021 : Endocrine (Springer) - Associated Editor
2014-2022: European Journal of Endocrinology (official Journal of ESE) - Associate Editor

IV– CLINICAL APPOINTMENTS
Since 2010: Azienda Policlinico Umberto I Dirigente Medico – DAI Medicina Interna – UOC – Endocrinologia (SMIC08).

V – TEACHING APPOINTMENTS
2008 Sapienza University of Rome Docenza di Fisiologia, Anatomia e Istologia nel Corso di Laurea CLUPS Infermieristica
2006 Sapienza University of Rome Docenza nella I° Scuola di Specializzazione in Endocrionologia e Malattie del Ricambio
2008 Sapienza University of Rome Affidamento nei corsi di Endocrinologia, Medicina della Riproduzione e Metodologia Medico-Scientifica presso la Facoltà di Medicina e Odontoiatria. Patologia Integrata III, V e Metodologia VIII
2010 Sapienza University of Rome Docenza nel Dottorato di Ricerca in Scienze Endocrinologiche, Metaboliche e Andrologiche
2013 Sapienza University of Rome Incardinamento in Endocrinologia per CLM in Comunicazione Scientifica Biomedica
2014 Sapienza University of Rome Responsible for the “Reproductive Medicine” for Applied Pathology V – CLMMC “F”
2016 Sapienza University of Rome Insegnamento di Endocrinologia Patologia III – CLMMC “A”

VI - SOCIETY MEMBERBERSHIPS, AWARDS AND HONORS
2001- Member of the British Endocrine Society (BES)
2002 Awarded with a Travel Grant (USD-1000) issued by the American Endocrine Society.
2002- Member of the Italian Society of Endocrinology (SIE)
2004- Academician of the European Academy of Andrology (EAA)
2004- Member of the Italian Society of Andrology and Sexual Medicine (SIAMS)
2004- Member of ESSM and ISSM (European and International Societies for Sexual Medicine)
2005 Winner of the "TRONCHETTI" Prize (€5000) issued by the Italian Society of Endocrinology (Società Italiana di Endocrinologia SIE) for the best research by investigators under the age of 30.
2005 Winner of the "Pietrandrea" Prize (€2000) issued by the Rotary Club for the best publication from young investigators.
2006 Winner of a Mobility (Exchange) Grant (€15000) for his international collaboration with the Endocrine Oncology Unit of the Queen Mary University of London, issued by the Italian Society of Endocrinology (Società Italiana di Endocrinologia SIE).
2007 Member of the “American Endocrine Society”(ENDO Society)
2008 Awarded with a Travel Grant (€1000) from the International Society of Endocrinology for his oral presentation to the Conference in Rio the Janeiro.
2008 Member of the “European Society of Endocrinology”(ESE)
2012 Best Oral Presentation at ESSM in Amsterdam (€2000).
2013 Awarded with the ISA Young Andrologist Award - ($1000) [The award is presented at the International Conference of Andrology held in Melbourne Feb 2013, Australia]. This is the most prestigious international award in the field of medical Andrology, given every 4 years to the few young researchers that produced outstanding achievements in the field.
2015 Winner of the "UNDER-40 CARRIER AWARD" (€5000) issued by the Italian Society of Endocrinology (Società Italiana di Endocrinologia SIE) for the best carrier of a researcher under the age of 40.

VII – RESEARCH ACTIVITY
My research activity has focused on steroid hormones – specifically androgens and glucorticoids- and their interactions with cardiovascular disorders.
I dedicated my early carrier exploring the interactions between adipokines, steroid hormones and gonadal steroidogenesis. Through basic and clinical experimental studies I discovered and characterized the molecular mechanism linking leptin to the 17-20-lyase activity of Leydig cells. Subsequently, I moved to investigate the effects of steroid hormonal therapies in male hypogonadism and female hyperandrogenism, and how these could impact on cardiovascular health. In this field my research team has pioneered the studies on androgens – type 5 phosphodiesterase interactions in vascular pathophysiology.
While in UK, I dedicated my research activity to glucocorticoid excess. In particular I investigated diagnostic tests, including imaging and pathophysiology of Cushing’s syndrome, with some original works, for example on ectopic Cushing’s syndrome, being among the most highly cited in the field.
Back to Rome, I brought my knowledge in diagnostic medicine and imaging learnt in UK and set up a diagnostic facility that is now producing exciding finding on steroid hormones’ neoplasm, including Leydig-cell tumors and testicular cancer. In Rome, I have continued clinical translational research in the field of glucocorticoids focusing on adrenal insufficiency and the interplay between glucocorticoids, the immune system and the clock-genes. I have also produced clinical works on various aspects of pituitary disorders and neuroendocrine tumors.
Through my research I believe I have merged different expertise in andrology, sexual medicine and endocrinology starting a research area dedicated to the role of PDE5i in cardiovascular function, tissue repair and cardiac remodeling and regeneration, that is currently ongoing with simultaneous basic and clinical translational approach.

VIII – RESEARCH OUTPUT BIBLIOMETRICS (updated November 2018)
Number of published articles 152
Total Impact factor 637,3 points
Total Citations 6346 (Scopus) 9672 (Google Scholar)
Hirsch (H) index 41 (Scopus) 52 (Google Scholar)
Author ID 55183511100 (Scopus Author ID)
Ranking in Italian TOP Scientists Position 76