Medicine and Surgery

C) APPLIED BIOLOGY Genetic Analysis of Development - Homeotic Genes, Polycomb Group Genes, and Trithorax Group Genes - Molecular Mechanisms of X-Chromosome Inactivation in Mammals - Molecular Mechanisms of Parental Imprinting - Organization and Expression of Immunoglobulin Genes Genetic Analysis of Differentiation - "Master" Genes and "Pioneer" Factors - Plasticity and Transdifferentiation. Epithelial-Mesenchymal Transition in Pathophysiology Cancer Genetics - Genes Involved in Cancer Development. Tumor Inheritance. Loss of Heterozygosity - Multiphasic Tumor Development - Cancer Epigenetics - Cancer Stem Cells Functional Genetics and Genome Editing - Transgenesis; Gene Targeting in Embryonic Stem Cells; CRISPR/Cas Approaches.

- Genetica. Un approccio molecolare - VI edizione (2024) - Russel PJ - Pearson - Genetica. Principi di analisi formale - VIII edizione (2021) - Griffiths et al. – Zanichelli Additional texts or scientific articles for further reading will be agreed with the teachers during the course