THREE-DIMENSIONAL MODELING

Course objectives

Main teaching objectives: • To have acquired the knowledge essential for the pharmacodynamic effects of the classes of drugs in relation to the mechanism of action, and to the adverse effects. • To have acquired the knowledge essential for making a reasoned choice of drugs in relation to pathological conditions. • Be aware of the possible influence of individual factors and of concomitant medication on pharmacological and / or therapeutic effect and of the risk-benefit ratio of drug therapy.

Channel 1
GIUSEPPE BATTAGLIA Lecturers' profile

Program - Frequency - Exams

Course program
Origin and Development of Drugs. Clinical Drug Trials: Good Clinical Practice Guidelines. Pharmacovigilance: Objectives and Methodology. Pharmacodynamics. G Protein-Coupled Receptors, Channel Receptors, Intracellular Receptors, Ion Channels. GABAergic, Serotonergic, Noradrenergic, Dopaminergic, Histaminergic, Cholinergic, and Glutamatergic Transmission. Biotechnological Drugs. Routes of Drug Administration. Pharmacokinetics: Absorption, Distribution, Metabolism, and Excretion. Pharmacokinetic Parameters. Generic and Biosimilar Drugs. Variability in Drug Effects Based on Genetics, Physiological and Pathological Conditions. Drugs in Children and the Elderly. Toxicology: General Principles. Treatment of the Poisoned Patient. Gender- and Genetics-Related Pharmacokinetic and Therapeutic Differences. Drugs and Pregnancy. Pharmacology of the Autonomic Nervous System. Drugs for Bronchial Asthma and COPD. Drugs for Peptic Ulcer; Antiemetics and Prokinetics; Constipating Agents; Drugs for Chronic Inflammatory Bowel Diseases. Drugs for Rheumatoid Arthritis. Pharmacology of Inflammatory Processes: NSAIDs; Antileukotriene Drugs; Corticosteroids; Antihistamines. Pharmacology of the Endocrine System: Antidiabetics; Drugs for Thyroid Disorders; Contraceptives. Antibiotics: Classification and Resistance. Cell Wall Inhibitors, Protein Synthesis Inhibitors, Folate Synthesis Inhibitors, Quinolones. Antivirals: Anti-Herpetic, Anti-Influenza, Anti-Hepatitis C, Antiretroviral Agents.
Books
Goodman & Gilman: The pharmacological Basis of Therapy XIV Ed, 2022, L. Brunton - R. Hilal Danan, C. Knollmann
Bibliography
Updated references provided during lectures
  • Academic year2025/2026
  • CourseMedicine and Surgery
  • CurriculumSingle curriculum
  • Year4th year
  • Semester2nd semester
  • SSDBIO/14
  • CFU4