Neurobiology

This teaching module is dealing with some molecular mechanisms recently identified that allow in the nervous system a different reading of the genetic information and that function as a bridge between genes and the environment. A) Knowledge and understanding to know the terminology used in molecular biology to know the micromolecules involved in the processes of neuronal gene expression control to understand the molecular mechanisms implicated in the generation of neural diversity and specificity to know mechanisms of gene expression regulation, with particular attention to the regulation induced by neuronal activation to know new generation techniques for the study of nucleic acids and their chemical modifications B) Ability to apply knowledge and understanding know how to use molecular biology terminology know how to evaluate the possible effects of epigenetic modifications and of the modulation of regulatory RNAs on gene expression know how to design molecules for potential applications for a better comprehension of mechanisms of neuronal regulation of gene expression and for therapy know how to design genetic models to understand normal and pathological processes