THREE-DIMENSIONAL MODELING

Course objectives

General skills Provide the knowledge of the main biochemical methods for analysing of the properties of a protein from its isolation to its structural and functional characterization with particular focus on proteins involved in neurodegenerative processes. Skills module I Knowledge of the main biochemical methods for analysis of the structural and functional properties of proteins Skills module II Knowledge of the biochemical properties of specific proteins involved in neurodegenerative processes. Specific skills (common to both modules) A) knowledge and understanding The student: - Knows the main techniques necessary for the biochemical characterization of proteins; - Knows the main proteins involved in neurodegenerative diseases B) ability to apply knowledge and understanding The student is able to: - understand and evaluate the impact of structural modifications of biological macromolecules on their biological function; - exploit the knowledge of biochemical techniques to investigate the role of proteins involved in neurodegeneration C) Making judgements - critical thinking through the study of biochemical methods and their application to structural and functional analysis of proteins - learning by questioning D) Communication skills The student is able to: -communicate what has been learned during the oral exam E) Learning skills - learning the specific terminology - be able to make the logical connections between the topics covered - be able to identify the most relevant topics

Channel 1
MARIA ROSARIA FULLONE Lecturers' profile

Program - Frequency - Exams

Course program
Model systems for the study of neurodegenerative processes Protein complexes involved in neurodegenerative processes Sistemi proteici coinvolved in neurodegerative processes Biochemistry of metals in neurodegenerative processes
Prerequisites
No formal propedeuticity is required. However, basic knowledge of biochemistry, molecular biology as well as of cellular biology is necessary
Books
Textbooks and teaching material are published on the Elearning 2 educational site at the web page http://elearning2.uniroma1.it
Frequency
The course is structured in frontal lectures and guided activities.Attendance is not mandatory
Exam mode
The aim of the exam is to test the level of knowledge and deepening of the topics of the course program and the reasoning skills developed by the student on issues related to biochemistry. The assessment is expressed in thirtieths (minimum grade 18). The exam is oral and the answers to the questions are evaluated both for the content and for the appropriate scientific language
Lesson mode
The course is structured in frontal lectures and guided activities
  • Academic year2025/2026
  • CourseNeurobiology
  • CurriculumSingle curriculum
  • Year1st year
  • Semester2nd semester
  • SSDBIO/10
  • CFU3