THREE-DIMENSIONAL MODELING

Course objectives

This teaching module I is about some recent aspects of epigenetic and post-transcriptional regulation of gene expression. Notions about methodologies and molecular mechanisms will be provided. Recent examples will be discussed. Knowledge and understanding The student: - Knows the terminology of molecular biology correctly; - Knows the molecular bases of biological systems and processes; - Know the mechanisms and the different levels of control of gene expression, and their integration; -It knows the basic techniques for the study of nucleic acids Ability to apply knowledge and understanding The student: - knows how to correctly use molecular biology terminology; - will be able to orientate itself in the understanding and design of approaches to modulation of gene expression for therapeutic or biotechnological purposes; - is able to use the knowledge on techniques for the study of nucleic acids to design an experiment in research.

Channel 1
ALESSANDRO FATICA Lecturers' profile

Program - Frequency - Exams

Course program
Complexity of the genome: coding and non-coding sequences, repeated sequences and transposons Epitranscriptomics RNA processing and degradation RNA Editing RNA export Translational regulation Quality control of the mRNA long non-coding RNAs Circular RNAs Model cell systems Genome editing and mouse genetics techniques
Prerequisites
Basic knowledge of molecular biology
Books
Reviews and lessons available on http://elearning2.uniroma1.it/
Frequency
Classroom lectures
Exam mode
Knowledge of the contents of the scientific works discussed and ability to report problems faced in class. Learning of regulatory processes and methodologies of the discipline. Connection capacity between the various biological processes analyzed. Ability to reprocess the acquired knowledge in a personal and critical way. Expressive properties of use, in particular, of specialized terminology.
  • Academic year2025/2026
  • CourseNeurobiology
  • CurriculumSingle curriculum
  • Year1st year
  • Semester2nd semester
  • SSDBIO/11
  • CFU3