ZEIN MERSINI BESHARAT

Corso di Laurea Magistrale in Medicina e chirurgia "B"

Insegnamento: Patologia e Fisiopatologia Generale I - Patologia Generale

Corso di Laurea Magistrale in Biotecnologie mediche

Insegnamento: Patologia Molecolare e Cellulare I

Corso di Laurea Magistrale in Scienze delle Professioni Sanitarie Tecniche Diagnostiche

Insegnamento: Metodologia di Ricerca

Moduli: Patologia Generale e Statistica Sanitaria

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Corso di Laurea in Tecniche di Radiologia Medica, per Immagini e Radioterapia

Insegnamento: Basi Cellulari e Molecolari della Vita

Modulo: Patologia Generale

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Ricevimento: Previo appuntamento concordato tramite e-mail: zeinmersini.besharat@uniroma1.it

WORK EXPERIENCE
2023–present – RTT Researcher, bioinformatics analyses in precision medicine.
2020–2023 – RTD‑A Researcher.
2020–present – Faculty Member of the PhD in “Network Oncology and Precision Medicine”, Sapienza University of Rome.
2018–2020 – Post‑doctoral researcher, University of Siena and Sapienza University of Rome.
2016–2018 – Post‑doctoral researcher, Laboratory of Oncogenomics, Department of Experimental Medicine.

EDUCATION AND TRAINING
2016 – PhD in Molecular Medicine.
2013 – Diploma of Electrical and Computer Engineering, Master of Engineering Communications with a focus on Biomedicine.

WORK ACTIVITIES

Research projects

Bioinformatics analyses using omics tools
Development of large‑scale approaches for expression data analyses from different platforms (next‑generation sequencing and assays).

Molecular oncology
Characterization of the molecular events involved in tumorigenesis, mainly focusing on solid tumors and deregulated pathways.

Hedgehog/Gli signaling pathway
Analysis of dysregulated mechanisms of the Hedgehog/Gli signaling pathway involved in neoplastic diseases.

Oncosuppressor and oncogenes
Identification of novel molecules as oncosuppressor or oncogenes.

MicroRNAs and epigenetic regulation
Identification of epigenetic networks including microRNAs and long non‑coding RNAs in tumors.

Circulating biomarkers
Analysis and discovery of circulating biomarkers (mainly microRNAs and cfDNA) in cancer.

Tumors and cancer treatments
Medulloblastoma, neuroblastoma, gliomas, lung, colorectal, thyroid cancers, melanoma, chemoresistance and immunotherapy.

AWARDS
Winner of Minerva Research Award III Edition for research on the role of microRNAs in cancer, Foundation Roma Sapienza (01.12.2021).
Winner of Post‑doctoral Fellowship, Fondazione Umberto Veronesi, year 2022 (26.11.2021).
Awarded the National Scientific Qualification for Associate Professor for SC 06/A2, SSD MED/04, Call 2018–2020, validity: 31/05/2021–31/05/2030.
Three‑year scholarship for completion of PhD in Molecular Medicine, Sapienza University of Rome (2013–2016).

COLLABORATIONS

Italian
Sapienza University (Department of Radiological, Oncological and Pathological Science; Department of Drug Chemistry and Technologies; Department of Molecular Medicine; Department of Informatics; Department of Computer, Control and Management Engineering; Department of Translational and Precision Medicine), Ospedale Pediatrico Bambino Gesù, University of Siena.

International
David H. Koch Institute for Integrative Cancer Research, MIT, Cambridge (MA), USA; Heidelberg University, Germany; University of Bern, Switzerland.

EDITORIAL ACTIVITY
International Scientific Board Member, Guest Editor of the Special Issue “Molecular Biomarkers in Cancer and Metabolic Disease”, International Journal of Molecular Sciences (2019–present).
International Scientific Board Member, Guest Editor of the Special Issue “Signalling pathways in Metabolic Diseases and Cancer”, Cancers (2019–present).

REFEREE OF INTERNATIONAL SCIENTIFIC JOURNALS
BMC Cancer; Cancer Management and Research; International Journal of Molecular Sciences; OncoTargets and Therapy; Frontiers in Cell and Developmental Biology; Diagnostics; Journal of Immunology Research; Cancers; Journal of Personalized Medicine; Biomedicines; Frontiers in Pharmacology.

Member of Expert Peer Reviewers for Italian Scientific Evaluation (REPRISE), Italian Ministry of Education, University and Research.

ORAL PRESENTATIONS
Montpellier (France), International LifeTime Conference.
Oral presentation: “Experimental disease models, Longitudinal samples and Data Integration”, Genopolys, Campus Arnaud de Villeneuve, 141 Rue de la Cardonille, 34396 Montpellier cedex 5.

INTERNATIONAL MEMBERSHIPS
2019–present – Member of the European Association for Cancer Research (EACR), Member ID EACR27439.
2014–present – Member of the European SIOP‑LGG preclinical working group (preclinical working group on low‑grade glioma, LGG, of the International Society of Pediatric Oncology, SIOP).

GRANTS
“Evaluation of circulating microRNAs in medulloblastoma as prognostic biomarkers”.
Sapienza University Research Grants 2019. Duration: 1 year. Principal Investigator: Besharat Zein Mersini. Amount: 3.000 €.

“Circulating microRNAs and DNA (cfDNA) as novel biomarkers for diagnostic, prognostic and therapeutic use in Medullary Thyroid Carcinoma”.
AIFA. PI: Prof. Elisabetta Ferretti. Amount: 983.497,87 €. Investigator: Besharat Zein Mersini.

ADDITIONAL INFORMATION

Researcher identifiers
Scopus Author ID: 56595254100
ORCID: 0000‑0003‑0317‑9854
ResearcherID: A‑3898‑2015
Google Scholar: Besharat ZM

Complete list of publications
Available at: https://www.scopus.com/authid/detail.uri?authorId=56595254100

Scientific production (first publication in 2014; reference period 2014–2026)
Total number of publications in international peer‑reviewed journals: 58
Book chapters: 2

Total Impact Factor (IF): 340.35 (IF publication year); 329.40 (IF 2024)
Average IF per paper: 5.97 (IF publication year); 5.49 (IF 2024)

Total citations: 1534 (Scopus); 1774 (Google Scholar)
Average citations per product: 25.56

H‑index: 22 (Scopus); 24 (Google Scholar).