corso|29862

Basics of the hypothalamus-pituitary-gonadal axis. Reminders of the physiology of the male and female gonads. Infertility and sterility: definitions and epidemiology. Causes of male infertility. Causes of female infertility. Causes common to both sexes. PMA techniques. Artificial insemination. IVF. GIFT. Additional techniques (ICSI, PICSI, IMSI, pre-implantation diagnosis, fertility preservation). Sperm collection and preparation. Main diagnostic tests performed on sperm. Notes on PMA legislation.

Basics of the reproductive system and sexual hormones.

L. Gandini, A. Lenzi: "Biotecnologie della riproduzione umana", Carocci Faber, Edizione: 2013. Collana: I Manuali.

Students are required to attend at least 2/3 of the lessons.

To pass the exam, the student must demonstrate to have acquired sufficient knowledge of the topics covered in class, and to be able to expose them in a clear way with language property.

Frontal teaching lessons including slide projection and videos.

The Elective Educational Activities (ADE) include six seminars whose programs are described below. Thyroid pathologies (Teacher Prof. Salvatore Ulisse, 2 CFU-24 hours) Overview of the pathophysiology of the thyroid gland and regulation of the hypothalamus-hypophysis-thyroid axis. Pathogenesis, diagnosis and therapy of hypothyroidism. Iodine deficiency disorders. Pathogenesis, diagnosis and therapy of hyperthyroidism. Risk factors associated with the onset of thyroid neoplasms (ionizing radiation, familiarity, iodine intake, etc.). Overview of the molecular pathogenesis of thyroid tumors. Main biochemical, genetic and instrumental diagnostic pathways used in the diagnosis of thyroid carcinomas. Staging systems and prognosis of patients affected by thyroid neoplasms. Infertility and assisted reproduction methods (Teacher Prof. Enke Baldini, 1 CFU-12 hours) Basics of the hypothalamus-pituitary-gonadal axis. Reminders of the physiology of the male and female gonads. Infertility and sterility: definitions and epidemiology. Causes of male infertility. Causes of female infertility. Causes common to both sexes. PMA techniques. Artificial insemination. IVF. GIFT. Additional techniques (ICSI, PICSI, IMSI, pre-implantation diagnosis, fertility preservation). Sperm collection and preparation. Main diagnostic tests performed on sperm. Notes on PMA legislation. The role of the nurse in the main pediatric infectious diseases (Teacher Prof. Alessandro Ferretti, 1 CFU – 12 hours) The Elective Teaching Activity focuses on the crucial role of nurses in managing the main infectious diseases in pediatric age. During the course, students will explore diseases such as measles, chickenpox and meningitis in depth, understanding the modes of transmission, main symptoms and preventive strategies. Attention will be paid to isolation techniques, symptom management and the importance of vaccination. Through case studies and simulations, students will learn to develop specific care plans, improving their skills in observation and emotional support of young patients and their families. The nurse, in this context, emerges as a key figure in the prevention of complications and in the promotion of pediatric public health. Nursing care for bariatric patients (Teacher Prof. Stefano Pontone, 1 CFU-12 hours) The aim of the Elective Teaching Activity is to address issues relating to obesity, clarifying epidemiology, etiology and treatment methods, with particular attention to nursing care in the three phases, pre-, intra- and post-operative. The topics relating to comorbidities and pre-operative weight management within the department and the patient's preparation for treatment will be explored in depth. Minimally invasive treatments for obesity and the role of the nurse in the management and control of the patient during the various therapeutic pathways will also be considered. Chemotherapy: antibacterial and antineoplastic (Teacher Prof. Sebastiano Alemà, 1 CFU-12 hours) Antibacterial chemotherapy General information on the classification of bacteria. General information on the different types of antibacterial therapy: sensitivity testing. Spectrum of activity, bactericidal/bacteriostatic effect. General information on the toxicity of antibacterial drugs: superinfections and hypersensitivity reactions. Bacterial resistance. The various types of resistance, the mechanisms and principles to minimize it. Classes of antibiotics: mechanisms of action, main indications and particular toxicities. Beta-lactams, protein synthesis inhibitors, sulphonamides and quinolones. Antineoplastic chemotherapy General information on oncology: epidemiology, etiology, classification of neoplasms. Principles of anti-neoplastic therapy: cell cycle, polychemotherapy. Mechanisms of action of the various classes of antineoplastic drugs: Alkylating agents, antibiotics, antimetabolites, topoisomerase inhibitors, antimitotics, endocrine therapy, biological therapy and targeted therapies. Generic toxicities of antiblastic drugs. Myelosuppression, emesis and organ toxicity. Ancillary supportive therapies, routes of administration and patient care. Antineoplastic drug resistance: mechanisms of action and strategies to minimize it.

It is important that the student has knowledge of biology, genetics, histology, anatomy and physiology of the main organs and systems of the human body.

ADE Prof. Ulisse - F. Monaco: “Endocrinology for Degree Courses in the Health Professions. Società Editrice Universo, 1st Edition 2008. Students will also be provided with slides and other in-depth material. ADE Prof. Baldini - L. Gandini, A. Lenzi: "Biotechnologies of human reproduction", Carocci Faber, Edition: 2013. Series: The Manuals. Students will also be provided with slides and other in-depth material. ADE Prof. Ferretti - Nelson's Paediatrics, 2 volumes. by Robert M. Kliegman, Joseph W. St Geme III, et al., 2023. Students will also be provided with all the slides necessary for the study/in-depth study of the topics. ADE Prof. Pontone - Students will be provided with all the slides necessary for the study/in-depth study of the topics covered. ADE Prof. Alemà - Rang-Dale, Pharmacology Chapters: Anti-tumor drugs, Basic Principles of Chemotherapy, Antibacterial agents.

To be able to support the suitability for a specific course it is necessary to have documented the presence in the classroom of at least 67% of the hours corresponding to the credits assigned to the integrated course. The attendance will be measured by roll call at the beginning of the lesson.

To pass an ADE the student needs to obtain a qualification. The student must demonstrate to have acquired sufficient knowledge of the topics covered in class, and to be able to expose them in a clear way with language property.

Lectures with the aid of "PowerPoint" presentations that will be made available to students.

ADE Antibacterial chemotherapy • General information on the classification of bacteria. • General information on the different types of antibacterial therapy: sensitivity tests. Spectrum of activity, bactericidal/bacteriostatic effect. • General information on the toxicity of antibacterial drugs: superinfections and hypersensitivity reactions • Bacterial resistance. The various types of resistance, the mechanisms and principles to minimize it • Classes of antibiotics: mechanisms of action, main indications and particular toxicities • Beta-lactams, protein synthesis inhibitors, sulphonamides and quinolones ADE Antineoplastic chemotherapy • General information on oncology: epidemiology, etiology, classification of neoplasms • Principles of anti-neoplastic therapy: cell cycle, polychemotherapy • Mechanisms of action of the various classes of antineoplastic drugs: Alkylating agents, antibiotics, antimetabolites, topoisomerase inhibitors, antimitotics, endocrine therapy, biological therapy and targeted therapies. • Generic toxicities of antiblastic drugs. Myelosuppression, emesis and organ toxicity • Ancillary supportive therapies, routes of administration and patient care • Antineoplastic drug resistance: mechanisms of action and strategies to minimize it

The necessary prerequisite is attendance of the course's Pharmacology lessons

Handouts taken from pharmacology textbooks or similar regarding the topics are provided to students

In order to obtain the ADE attendance certificate, it is necessary to complete a multiple choice test on the topics covered

In order to obtain the ADE attendance certificate, it is necessary to complete a multiple choice test on the topics covered

The presentations on the topics covered are preceded by the presentation of a clinical case and end with the performance of short critical reasoning exercises in plenary

Fever: Recognition, Detection, When and How to Treat Fever of Unknown Origin: Definition and Diagnostic/Therapeutic Management Common and Re-emerging Infectious Pathogens Vaccinations

Knowledge of developmental physiology, general and specialized pathology. Nursing approach to the pediatric patient and their caregivers, focusing on signs and symptoms to observe, collection of vital parameters, and alarm signs to monitor. Effective management of nursing and medical care needs of pediatric patients.

• Slides provided to students with bibliographic references included in the slides • Pediatria: principi e pratica clinica. Terza edizione di maurizio guglielmi, giorgio bartolozzi • Nelson. Manuale di pediatria. Sesta edizione di karen j. Marcdante, robert m. Kliegman, hal b. Jenson, richard e. Behrman

Frequency in location

Assessment and collegial discussion with all students during lessons.

• Lectures for students with the use of slides.