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Educational objectives Bioactive and pharmacologically active organic molecules belong to a wide, structurally various group of compounds, featuring high added value and interesting industrial potential application. The main groups of natural biologically and pharmacologically active products will be illustrated, together with some important synthetic derivatives and analogues. Modern synthetic methodologies for the obtaining of biocative products will be described. General educational objectives of the course are: to confer knowledge of the main bioactivity features of various classes of natural and synthetic organic compounds, to confer knowledge of the principles of pharmaceutical and medicinal chemistry. At the end of the course (specific objectives) students will be able to: have a wider knowledge of metabolic pathways from which bioactive organic products come from in nature; have a general knowledge of structure activity relationship (SAR) applied to bioactive and pharmacological active organic compounds. As expected results of the learning path, students will be able to describe metabolic pathways leading to bioactive compounds and to relate bioactivities to functional groups and chemical structures; to expand their knowledge in the field of medicinal chemistry and of modern synthetic methodologies applied to the preparation of bioactive molecules; to improve their expertise in correct scientific communication.